Acute Coronary Syndromes in Women: A Narrative Review of Sex-Specific Characteristics.

IF 2.2 3区医学 Q2 PERIPHERAL VASCULAR DISEASE Angiology Pub Date : 2025-03-01 Epub Date: 2023-11-23 DOI:10.1177/00033197231218331

Panagiotis Theofilis, Panayotis K Vlachakis, Emmanouil Mantzouranis, Athanasios Sakalidis, Christina Chrysohoou, Ioannis Leontsinis, George Lazaros, Kyriakos Dimitriadis, Maria Drakopoulou, Aikaterini Vordoni, Evangelos Oikonomou, Konstantinos Tsioufis, Dimitris Tousoulis

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Abstract

Acute coronary syndromes (ACSs) encompass a spectrum of life-threatening cardiovascular conditions, including unstable angina (UA) and myocardial infarction. While significant progress has been made in the understanding and management of ACS over the years, it has become increasingly evident that sex-based differences play a pivotal role in the pathophysiology, presentation, and outcomes of these conditions. Despite this recognition, the majority of clinical research in the field has historically focused on male populations, leading to a significant knowledge gap in understanding the unique aspects of ACS in women. This review article aims to comprehensively explore and synthesize the current body of literature concerning the sex-specific characteristics of ACS, shedding light on the epidemiology, risk factors, clinical presentation, diagnostic challenges, treatment strategies, and prognosis in women. By elucidating the distinct aspects of ACS in women, this review intends to foster greater awareness and improved clinical management, ultimately contributing to enhanced cardiovascular care for female patients.

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女性急性冠状动脉综合征:性别特异性特征的叙述性回顾。

急性冠状动脉综合征(ACSs)包括一系列危及生命的心血管疾病，包括不稳定型心绞痛(UA)和心肌梗死。虽然多年来在ACS的理解和管理方面取得了重大进展，但越来越明显的是，性别差异在这些疾病的病理生理、表现和结果中起着关键作用。尽管认识到这一点，但该领域的大多数临床研究历史上都集中在男性人群上，导致对女性ACS独特方面的理解存在重大知识差距。本文旨在对ACS的性别特征、流行病学、危险因素、临床表现、诊断挑战、治疗策略和预后等方面的文献进行综述和综合。通过阐明女性ACS的不同方面，本综述旨在提高对ACS的认识和改进临床管理，最终有助于提高女性患者的心血管护理水平。

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来源期刊

Angiology 医学-外周血管病

CiteScore

5.50

自引率

14.30%

发文量

180

审稿时长

6-12 weeks

期刊介绍： A presentation of original, peer-reviewed original articles, review and case reports relative to all phases of all vascular diseases, Angiology (ANG) offers more than a typical cardiology journal. With approximately 1000 pages per year covering diagnostic methods, therapeutic approaches, and clinical and laboratory research, ANG is among the most informative publications in the field of peripheral vascular and cardiovascular diseases. This journal is a member of the Committee on Publication Ethics (COPE). Average time from submission to first decision: 13 days