Measuring symptom prevalence, severity and distress of cancer survivors

Karis K.F. Cheng , David R. Thompson , W.M. Ling , Carmen W.H. Chan
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引用次数: 32

Abstract

The purpose of this paper is to describe patients’ self-reported symptom occurrence, symptom intensity and symptom distress at post-treatment of cancer therapy. A total of 243 outpatients with heterogeneous solid tumours within 12 months following the completion of initial cancer treatment (chemotherapy or radiotherapy) were assessed using the Chinese version of the Memorial Symptom Assessment Scale (MSAS). The mean age of the sample was 54.2 ± 12 and over half (57.6%) were women. The most common diagnoses were breast cancer (26.3%) and colon cancer (23.5%). The median number of symptoms per patient was 8 (range 0–23 symptoms) and the most prevalent were dry mouth (49.8%), lack of energy (46.9%), worry (39.1%), pain (35%) and feeling drowsy (33.7%). The mean symptom severity and distress scores measured on the MSAS were 1.92 ± 0.2 (range 1.7–2.3) and 1.37 ± 0.3 (.9–2), respectively. The prevalence of certain symptoms was influenced by the primary site of cancer. Pain, worrying and difficulty in swallowing were the most clinically important symptoms. In conclusion, intense physical and psychological symptoms were highly prevalent and distressing to cancer survivors. Comprehensive symptoms assessment is a requisite toward effective symptom control.

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测量癌症幸存者的症状患病率、严重程度和痛苦程度
本文的目的是描述癌症治疗后患者自我报告的症状发生、症状强度和症状困扰。采用中文版记忆症状评估量表(MSAS)对243例非均质实体瘤患者在完成初始癌症治疗(化疗或放疗)后12个月内的临床表现进行评估。样本的平均年龄为54.2±12岁,超过一半(57.6%)为女性。最常见的诊断是乳腺癌(26.3%)和结肠癌(23.5%)。每位患者的症状中位数为8(范围为0-23),最常见的是口干(49.8%)、精力不足(46.9%)、焦虑(39.1%)、疼痛(35%)和困倦(33.7%)。MSAS的平均症状严重程度和痛苦评分分别为1.92±0.2(范围1.7-2.3)和1.37±0.3(范围0.9 - 2)。某些症状的出现受癌症原发部位的影响。疼痛、焦虑和吞咽困难是最重要的临床症状。总之,对癌症幸存者来说,强烈的身体和心理症状是非常普遍和痛苦的。全面的症状评估是有效控制症状的必要条件。
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