[Short bowel syndrome and glucose tolerance].

U Fleck, W Nowak, L Senf
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Abstract

There are different signs after extended small bowel resection. The length of the resected small intestine (size of resection), the location of the removed part (type of resection), the time after operation (stage of adaption) and the age of the patient define the severity and nature of complaints following small bowel resections. We examined the dynamics of glucose- and insulin level after oral and intravenous glucose administration to recognize the relation to the size of resection. We found a decreased basal insulin concentration and a diminished response of insulin after intravenous glucose load in patients with extensive small bowel resection. This reduced response after parenteral administration of glucose load we did not find in the ileum-resected group compared to control group. We can conclude, it is possible to get information about the size of small bowel resections by the intravenous glucose tolerance test.

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[短肠综合征和葡萄糖耐量]。
延长小肠切除术后有不同的征象。切除小肠的长度(切除的大小)、切除部位的位置(切除的类型)、手术后的时间(适应阶段)和患者的年龄决定了小肠切除术后主诉的严重程度和性质。我们检查了口服和静脉注射葡萄糖后葡萄糖和胰岛素水平的动态变化,以识别与切除大小的关系。我们发现,在广泛小肠切除术的患者中,静脉葡萄糖负荷后,基础胰岛素浓度降低,胰岛素反应减弱。与对照组相比,我们在回肠切除组没有发现肠外给药葡萄糖负荷后反应降低。我们可以得出结论,通过静脉葡萄糖耐量试验可以获得小肠切除术大小的信息。
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