A simple coronary CT angiography-based jeopardy score for the identification of extensive coronary artery disease: Validation against invasive coronary angiography

IF 4.9 2区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Diagnostic and Interventional Imaging Pub Date : 2023-11-25 DOI:10.1016/j.diii.2023.11.001

Jan A. Schaab , Alessandro Candreva , Alexia Rossi , Susanne Markendorf , Dominik Sager , Michael Messerli , Aju P. Pazhenkottil , Dominik C. Benz , Philipp A. Kaufmann , Ronny R. Buechel , Barbara E. Stähli , Andreas A. Giannopoulos

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Abstract

Purpose

The invasive British Cardiovascular Intervention Society Jeopardy Score (iBCIS-JS) is a simple angiographic scoring system, enabling quantification of the extent of jeopardized myocardium related to clinically significant coronary artery disease (CAD). The purpose of this study was to develop and validate the coronary CT angiography-based BCIS-JS (CT-BCIS-JS) against the iBCIS-JS in patients with suspected or stable CAD.

Materials and methods

Patients who underwent coronary CT angiography followed by invasive coronary angiography, within 90 days were retrospectively included. CT-BCIS-JS and iBCIS-JS were calculated, with a score ≥ 6 indicating extensive CAD. Correlation between the CT-BCIS-JS and iBCIS-JS was searched for using Spearman's coefficient, and agreement with weighted Kappa (κ) analyses.

Results

A total of 122 patients were included. There were 102 men and 20 women with a median age of 62 years (Q1, Q3: 54, 68; age range: 19–83 years). No differences in median CT-BCIS-JS (4; Q1, Q3: 0, 8) and median iBCIS-JS (4; Q1, Q3: 0, 8) were found (P = 0.18). Extensive CAD was identified in 53 (43.4%) and 52 (42.6%) patients using CT-BCIS-JS and iBCIS-JS, respectively (P = 0.88). CT-based and iBCIS-JS showed excellent correlation (r = 0.98; P < 0.001) and almost perfect agreement (κ = 0.93; 95% confidence interval: 0.90–0.97). Agreement for identification of an iBCIS-JS ≥ 6 was almost perfect (κ = 0.94; 95 % confidence interval: 0.87–0.99).

Conclusion

The CT-BCIS-JS represents a feasible, and accurate method for quantification of CAD, with capabilities not different from those of iBCIS-JS. It enables simple, non-invasive identification of patients with anatomically extensive CAD.

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基于简单冠状动脉CT血管造影的危险评分用于广泛冠状动脉疾病的识别:对侵入性冠状动脉造影的验证

目的:有创性英国心血管介入学会危险评分(iBCIS-JS)是一种简单的血管造影评分系统，可以量化与临床显著性冠状动脉疾病(CAD)相关的心肌损害程度。本研究的目的是开发和验证基于冠状动脉CT血管造影的BCIS-JS (CT-BCIS-JS)对疑似或稳定型CAD患者的iBCIS-JS的疗效。材料和方法:回顾性分析90天内行冠状动脉CT血管造影并行有创冠状动脉造影的患者。计算CT-BCIS-JS和iBCIS-JS，评分≥6分提示广泛的CAD。CT-BCIS-JS与iBCIS-JS的相关性采用Spearman系数分析，并与加权Kappa (κ)分析一致。结果:共纳入122例患者。102名男性和20名女性，中位年龄为62岁(Q1, Q3: 54,68;年龄:19-83岁)。CT-BCIS-JS中位数无差异(4;Q1, Q3: 0,8)和中位iBCIS-JS (4;Q1, Q3: 0,8) (P = 0.18)。CT-BCIS-JS和iBCIS-JS分别在53例(43.4%)和52例(42.6%)患者中发现了广泛的CAD (P = 0.88)。CT-based与iBCIS-JS具有极好的相关性(r = 0.98;P结论:CT-BCIS-JS是一种可行、准确的CAD量化方法，其功能与iBCIS-JS无异。它可以简单，非侵入性地识别解剖广泛的CAD患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diagnostic and Interventional Imaging Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

8.50

自引率

29.10%

发文量

126

审稿时长

11 days

期刊介绍： Diagnostic and Interventional Imaging accepts publications originating from any part of the world based only on their scientific merit. The Journal focuses on illustrated articles with great iconographic topics and aims at aiding sharpening clinical decision-making skills as well as following high research topics. All articles are published in English. Diagnostic and Interventional Imaging publishes editorials, technical notes, letters, original and review articles on abdominal, breast, cancer, cardiac, emergency, forensic medicine, head and neck, musculoskeletal, gastrointestinal, genitourinary, interventional, obstetric, pediatric, thoracic and vascular imaging, neuroradiology, nuclear medicine, as well as contrast material, computer developments, health policies and practice, and medical physics relevant to imaging.