Influenza vaccine: a review on current scenario and future prospects.

IF 3.6 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Journal, genetic engineering & biotechnology Pub Date : 2023-11-30 DOI:10.1186/s43141-023-00581-y
Dipanshi Gupta, Sumedha Mohan
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Abstract

Vaccination is a crucial tool in preventing influenza, but it requires annual updates in vaccine composition due to the ever-changing nature of the flu virus. While healthcare and economic burdens have reduced, the virus remains a challenge. Research conducted over the past decade has revealed pathways for improvement through both basic and clinical studies. Viral surveillance plays a vital role in the better selection of candidate viruses for vaccines and the early detection of drug-resistant strains.This page offers a description of future vaccine developments and an overview of current vaccine options. In the coming years, we anticipate significant changes in vaccine production, moving away from traditional egg-based methods towards innovative technologies such as DNA and RNA vaccines. These newer approaches offer significant advantages over traditional egg-based and cell culture-based influenza vaccine manufacturing.

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流感疫苗:现状和未来展望综述。
疫苗接种是预防流感的重要工具,但由于流感病毒的性质不断变化,需要每年更新疫苗成分。虽然医疗和经济负担有所减轻,但该病毒仍然是一个挑战。过去十年进行的研究已经通过基础和临床研究揭示了改善的途径。病毒监测在更好地选择疫苗候选病毒和早期发现耐药菌株方面起着至关重要的作用。本页提供了对未来疫苗发展的描述和当前疫苗选择的概述。在未来几年中,我们预计疫苗生产将发生重大变化,从传统的基于鸡蛋的方法转向DNA和RNA疫苗等创新技术。与传统的基于鸡蛋和细胞培养的流感疫苗生产相比,这些新方法具有显著的优势。
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