Effect of Yoga and Walking on Glycemic Control for the Management of Type 2 Diabetes: A Systematic Review and Meta-analysis.

IF 0.6 Q4 ENDOCRINOLOGY & METABOLISM Journal of the ASEAN Federation of Endocrine Societies Pub Date : 2023-01-01 Epub Date: 2023-09-19 DOI:10.15605/jafes.038.02.20
Biswajit Dhali, Sridip Chatterjee, Sudip Sundar Das, Mary D Cruz
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Abstract

Background: A daily habit of yogic practice or walking, along with an oral hypoglycemic agent (OHA) could be beneficial for better control of type 2 diabetes mellitus (T2DM). We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to find out the efficiency of yoga or walking on glycemic control in T2DM.

Methodology: The present systematic review and meta-analysis were completed according to the PRISMA guidelines. The risk of bias in included studies was evaluated, by using the revised Cochrane risk-of-bias tool for randomized trials. Meta-analysis was implemented using RevMan software. Forest plots were used to illustrate the study findings and meta-analysis results.

Results: Sixteen studies were included in this systematic review, where 1820 participants were allocated to one of the following interventions: yoga, walking, and without any regular exercise (control group). Participants were between 17-75 years of age. Compared to the control group, the yoga group had a significant reduction in fasting blood glucose (FBG) by 31.98 mg/dL (95% CI = -47.93 to -16.03), postprandial blood glucose (PPBG) by 25.59 mg/dL (95% CI = -44.00 to -7.18], glycosylated hemoglobin (HbAlc) by 0.73% (95% CI = -1.24 to -0.22), fasting insulin by 7.19 μIU/mL (95% CI = -12.10 to -2.28), and homeostatic model assessment for insulin resistance (HOMA-IR) by 3.87 (95% CI = -8.40 to -0.66). Compared to the control group, the walking group had a significant reduction in FBG by 12.37 mg/dL (95% CI = -20.06 to -4.68) and HbA1c by 0.35% (95% CI = -0.70 to -0.01). Compared to the walking group, the yoga group had a significant reduction in FBG by 12.07 mg/dL (95% CI = -24.34 to - 0.20), HbA1c by 0.20% (95% CI = -0.37 to -0.04), fasting insulin by 10.06 μIU/mL (95% CI = -23.84 to 3.71) and HOMA-IR by 5.97 (95% CI = -16.92 to 4.99).

Conclusions: Yoga or walking with OHA has positive effects on glycemic control. For the management of T2DM, yoga has relatively more significant effects on glycemic control than walking.Review registration number: PROSPERO registration number CRD42022310213.

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瑜伽和步行对2型糖尿病血糖控制的影响:一项系统综述和荟萃分析
背景:每天练习瑜伽或散步的习惯,以及口服降糖药(OHA)可能有利于更好地控制2型糖尿病(T2DM)。我们对随机对照试验(rct)进行了系统回顾和荟萃分析,以找出瑜伽或步行对T2DM患者血糖控制的有效性。方法学:本系统评价和荟萃分析是根据PRISMA指南完成的。采用改进的Cochrane随机试验偏倚风险工具,对纳入研究的偏倚风险进行评估。采用RevMan软件进行meta分析。森林样地用于说明研究结果和meta分析结果。结果:本系统综述纳入了16项研究,其中1820名参与者被分配到以下干预措施之一:瑜伽,散步和没有任何常规运动(对照组)。参与者年龄在17-75岁之间。与对照组相比,瑜伽组空腹血糖(FBG)降低31.98 mg/dL (95% CI = -47.93 ~ -16.03),餐后血糖(PPBG)降低25.59 mg/dL (95% CI = -44.00 ~ -7.18),糖化血红蛋白(HbAlc)降低0.73% (95% CI = -1.24 ~ -0.22),空腹胰岛素降低7.19 μIU/mL (95% CI = -12.10 ~ -2.28),胰岛素抵抗稳态模型评估(HOMA-IR)降低3.87 (95% CI = -8.40 ~ -0.66)。与对照组相比,步行组的FBG显著降低了12.37 mg/dL (95% CI = -20.06至-4.68),HbA1c显著降低了0.35% (95% CI = -0.70至-0.01)。与步行组相比,瑜伽组空腹血糖显著降低12.07 mg/dL (95% CI = -24.34 ~ - 0.20),糖化血红蛋白显著降低0.20% (95% CI = -0.37 ~ -0.04),空腹胰岛素显著降低10.06 μIU/mL (95% CI = -23.84 ~ 3.71), HOMA-IR显著降低5.97 (95% CI = -16.92 ~ 4.99)。结论:OHA伴瑜伽或步行对血糖控制有积极作用。对于2型糖尿病的治疗,瑜伽的血糖控制效果比步行更为显著。审核注册号:普洛斯彼罗注册号CRD42022310213。
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来源期刊
CiteScore
1.20
自引率
0.00%
发文量
22
审稿时长
8 weeks
期刊介绍: The Journal of the ASEAN Federation of Endocrine Societies (JAFES) is an OPEN ACCESS, internationally peer-reviewed, English language, medical and health science journal that is published in print two times a year by the ASEAN Federation of Endocrine Societies. It shall serve as the endocrine window between the ASEAN region and the world, featuring original papers and publishing key findings from specialists and experts of endocrinology.
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