Shrey Kapoor, Anna Kolchinski, Aaron M Gusdon, Lavienraj Premraj, Sung-Min Cho
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引用次数: 0
Abstract
Extracorporeal membrane oxygenation (ECMO) is a life-saving intervention for patients with refractory cardiorespiratory failure. Despite its benefits, ECMO carries a significant risk of neurological complications, including acute brain injury (ABI). Although standardized neuromonitoring and neurological care have been shown to improve early detection of ABI, the inability to perform neuroimaging in a timely manner is a major limitation in the accurate diagnosis of neurological complications. Therefore, blood-based biomarkers capable of detecting ongoing brain injury at the bedside are of great clinical significance. This review aims to provide a concise review of the current literature on plasma biomarkers for ABI in patients on ECMO support.
体外膜肺氧合（ECMO）是一种挽救难治性心肺功能衰竭患者生命的干预措施。尽管 ECMO 有诸多益处，但它也有很大的神经系统并发症风险，包括急性脑损伤 (ABI)。尽管标准化的神经监测和神经护理已被证明可提高 ABI 的早期检测率，但无法及时进行神经影像学检查是准确诊断神经系统并发症的主要限制因素。因此，能够在床边检测正在发生的脑损伤的血液生物标记物具有重要的临床意义。本综述旨在简明扼要地综述目前有关 ECMO 支持患者 ABI 血浆生物标志物的文献。
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