Medication Related-Problems and Associated Factors Among Patients with Hypertension at a Tertiary Care Hospital in Ethiopia: A Prospective Interventional Study.

IF 1.5 Q3 PERIPHERAL VASCULAR DISEASE Integrated Blood Pressure Control Pub Date : 2023-11-30 eCollection Date: 2023-01-01 DOI:10.2147/IBPC.S434072
Aster Wakjira Garedow, Mekonnen Damessa Mamo, Gorfineh Teshome Tesfaye
{"title":"Medication Related-Problems and Associated Factors Among Patients with Hypertension at a Tertiary Care Hospital in Ethiopia: A Prospective Interventional Study.","authors":"Aster Wakjira Garedow, Mekonnen Damessa Mamo, Gorfineh Teshome Tesfaye","doi":"10.2147/IBPC.S434072","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Hypertension affects more than 1.4 billion people worldwide currently, with that number anticipated to climb to 1.6 billion by 2025 with high mortality and morbidity effects. Medication related problems in cardiovascular disease patients, especially among hypertension patients were found to be high and a critical problem which is associated with high mortality, complication, prolonged hospital stay, compromised quality of life and increase health care cost.</p><p><strong>Objective: </strong>To determine medication related problems and its predictors among hypertension patients on chronic follow-up at Jimma Medical Center.</p><p><strong>Methods: </strong>A prospective interventional study was conducted among hypertension patients from November 28, 2021 to June 30, 2022 at Jimma Medical Center. Medication related problems were classified and identified based on Pharmaceutical care network Europe drug classification tool version 9.0. Interventions were done through discussion with individual prescriber and patients. Consecutive sampling technique was used. Binary Logistic regression was used to identify independent predictors of medication related problems. Variables having P-values < 0.05 were considered statistically significant.</p><p><strong>Results: </strong>Among 384 hypertension patients included in the study, 219 (57.1%) were male. The mean (SD) age was 49.06+17.79. Two thirds of study participants had at least one medication related problem. A total of 483 MRPs were identified among 231 (60.15%) patients. Treatment effectiveness related problem (55.48%) was the most common observed medication related problems. Alcoholism (AOR; 3.15, 95% CI [1.46-7.23]), stage II hypertension (AOR=2.77, 95% CI= [3.53-4.66]); comorbidity (AOR=2.88, 95% CI= [1.47-5.66]) and polypharmacy (AOR=3.07, 95% CI= [1.57-5.99]) were the independent predictors of medication related problems.</p><p><strong>Conclusion: </strong>The prevalence of medication related problems was high among hypertensive patients. Alcoholism, stage II hypertension, comorbidity and poly-pharmacy were the predictors of medication related problems. Therefore, to overcome the problems, clinical pharmacists, physicians and other health care professionals have to work in collaboration.</p>","PeriodicalId":45299,"journal":{"name":"Integrated Blood Pressure Control","volume":"16 ","pages":"123-136"},"PeriodicalIF":1.5000,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695137/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Integrated Blood Pressure Control","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/IBPC.S434072","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Hypertension affects more than 1.4 billion people worldwide currently, with that number anticipated to climb to 1.6 billion by 2025 with high mortality and morbidity effects. Medication related problems in cardiovascular disease patients, especially among hypertension patients were found to be high and a critical problem which is associated with high mortality, complication, prolonged hospital stay, compromised quality of life and increase health care cost.

Objective: To determine medication related problems and its predictors among hypertension patients on chronic follow-up at Jimma Medical Center.

Methods: A prospective interventional study was conducted among hypertension patients from November 28, 2021 to June 30, 2022 at Jimma Medical Center. Medication related problems were classified and identified based on Pharmaceutical care network Europe drug classification tool version 9.0. Interventions were done through discussion with individual prescriber and patients. Consecutive sampling technique was used. Binary Logistic regression was used to identify independent predictors of medication related problems. Variables having P-values < 0.05 were considered statistically significant.

Results: Among 384 hypertension patients included in the study, 219 (57.1%) were male. The mean (SD) age was 49.06+17.79. Two thirds of study participants had at least one medication related problem. A total of 483 MRPs were identified among 231 (60.15%) patients. Treatment effectiveness related problem (55.48%) was the most common observed medication related problems. Alcoholism (AOR; 3.15, 95% CI [1.46-7.23]), stage II hypertension (AOR=2.77, 95% CI= [3.53-4.66]); comorbidity (AOR=2.88, 95% CI= [1.47-5.66]) and polypharmacy (AOR=3.07, 95% CI= [1.57-5.99]) were the independent predictors of medication related problems.

Conclusion: The prevalence of medication related problems was high among hypertensive patients. Alcoholism, stage II hypertension, comorbidity and poly-pharmacy were the predictors of medication related problems. Therefore, to overcome the problems, clinical pharmacists, physicians and other health care professionals have to work in collaboration.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
埃塞俄比亚一家三级医院高血压患者的用药相关问题及相关因素:一项前瞻性干预研究。
背景:目前,全球有超过 14 亿人受到高血压的影响,预计到 2025 年这一数字将攀升至 16 亿,死亡率和发病率都将居高不下。研究发现,心血管疾病患者,尤其是高血压患者的用药相关问题较多,而且是一个与高死亡率、并发症、住院时间延长、生活质量下降和医疗费用增加相关的关键问题:确定吉马医疗中心长期随访的高血压患者中与用药相关的问题及其预测因素:吉马医疗中心于 2021 年 11 月 28 日至 2022 年 6 月 30 日对高血压患者进行了前瞻性干预研究。根据欧洲药物护理网络药物分类工具 9.0 版对与药物相关的问题进行了分类和识别。通过与开处方者和患者的讨论进行干预。采用了连续抽样技术。二元逻辑回归用于确定药物相关问题的独立预测因素。P值小于0.05的变量被认为具有统计学意义:在纳入研究的 384 名高血压患者中,219 人(57.1%)为男性。平均(标清)年龄为 49.06+17.79。三分之二的研究参与者至少有一个药物相关问题。在 231 名(60.15%)患者中,共发现了 483 个 MRP。治疗效果相关问题(55.48%)是最常见的药物相关问题。酗酒(AOR;3.15,95% CI=[1.46-7.23])、II 期高血压(AOR=2.77,95% CI=[3.53-4.66])、合并症(AOR=2.88,95% CI=[1.47-5.66])和多重用药(AOR=3.07,95% CI=[1.57-5.99])是药物相关问题的独立预测因素:结论:高血压患者中药物相关问题的发生率很高。结论:在高血压患者中,药物相关问题的发生率很高,酗酒、高血压 II 期、合并症和多种药物是药物相关问题的预测因素。因此,要解决这些问题,临床药剂师、医生和其他医护人员必须通力合作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Integrated Blood Pressure Control
Integrated Blood Pressure Control PERIPHERAL VASCULAR DISEASE-
CiteScore
4.60
自引率
0.00%
发文量
13
审稿时长
16 weeks
期刊最新文献
Prevalence and Predictors of Depression Symptoms Among Afghan Hypertensive Patients: Secondary Analysis of a Multi-Center Cross-Sectional Study. Prevalence of Risk Factors for Hypertension Among Faculty at an Urban University in Uganda [Response to Letter]. Resistance Training in Cardiovascular Diseases: A Review on Its Effectiveness in Controlling Risk Factors. Thoughts on "Prevalence of Risk Factors for Hypertension Among Faculty at an Urban University in Uganda" [Letter]. Adherence to Lifestyle Modification Practices and Its Associated Factors Among Hypertensive Patients in Bahir Dar City Hospitals, North West Ethiopia [Letter].
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1