Efficacy and safety of drugs used for 'assisted dying'.

IF 6.7 2区 医学 Q1 Medicine British medical bulletin Pub Date : 2022-07-09 DOI:10.1093/bmb/ldac009
Ana Worthington,Ilora Finlay,Claud Regnard
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引用次数: 4

Abstract

BACKGROUND 'Assisted dying' is practiced in some European countries and US states. Legislation suggests that there exists an easily prescribed drug which consistently brings about death quickly and painlessly. Evidence from jurisdictions where 'assisted dying' is practiced, however, reveals that hastening patient death is not so simple. SOURCES OF DATA This report is a collation of assisted suicide and euthanasia drug protocols published by the Canadian Association of MAiD Assessors and Providers and the Royal Dutch Medical Association, annual data reports from the USA and Canada and relevant academic publications pertaining to methods of 'assisted dying' in the USA, Belgium, Canada and Switzerland. AREAS OF AGREEMENT A wide variety of lethal drug combinations are used for people who want their life ended, and the prevalence of complications and failures in intentionally ending life suggest that 'assisted dying' applicants are at risk of distressing deaths. AREAS OF CONTROVERSY The efficacy and safety of 'assisted dying' drugs are currently difficult to assess, as clinician reporting is often very low. GROWING POINTS The findings from this report reveal that little attention has been given to the problem of unmonitored prescribing and administering of lethal drug combinations, whose mode of action is unclear. AREAS TIMELY FOR DEVELOPING RESEARCH In order to properly assess the efficacy and safety of 'assisted dying', a more thorough means of data collection regarding the drugs used must be implemented and research is urgently needed into their mode of action.
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用于“协助死亡”的药物的有效性和安全性。
“辅助死亡”在一些欧洲国家和美国各州实行。立法表明,存在一种容易开处方的药物,它总是迅速而无痛地导致死亡。然而,来自实施“协助死亡”的司法管辖区的证据表明,加速病人的死亡并没有那么简单。数据来源本报告整理了加拿大MAiD评估人员和提供者协会和荷兰皇家医学协会发表的协助自杀和安乐死药物协议,美国和加拿大的年度数据报告以及美国,比利时,加拿大和瑞士有关“协助死亡”方法的相关学术出版物。达成一致的领域各种各样的致命药物组合被用于想要结束生命的人,而故意结束生命的并发症和失败的普遍存在表明,“协助死亡”的申请人面临着痛苦死亡的风险。争议领域“辅助死亡”药物的有效性和安全性目前很难评估,因为临床医生的报告通常很低。这份报告的发现表明,致命药物组合的处方和使用不受监督的问题几乎没有得到重视,这些药物的作用方式尚不清楚。及时开展研究的领域为了正确评估“辅助死亡”的有效性和安全性,必须实施一种更彻底的关于所使用药物的数据收集方法,并且迫切需要研究它们的作用模式。
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来源期刊
British medical bulletin
British medical bulletin 医学-医学:内科
CiteScore
13.10
自引率
1.50%
发文量
24
审稿时长
>12 weeks
期刊介绍: British Medical Bulletin is a multidisciplinary publication, which comprises high quality reviews aimed at generalist physicians, junior doctors, and medical students in both developed and developing countries. Its key aims are to provide interpretations of growing points in medicine by trusted experts in the field, and to assist practitioners in incorporating not just evidence but new conceptual ways of thinking into their practice.
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