Jetske van der Schaar, Leonie N.C. Visser, Femke H. Bouwman, Philip Scheltens, Annelien L. Bredenoord, Wiesje M. van der Flier
{"title":"Considerations regarding a diagnosis of Alzheimer’s Disease before dementia: a systematic review","authors":"Jetske van der Schaar, Leonie N.C. Visser, Femke H. Bouwman, Philip Scheltens, Annelien L. Bredenoord, Wiesje M. van der Flier","doi":"10.1101/2021.09.16.21263690","DOIUrl":null,"url":null,"abstract":"<strong>Introduction</strong> The NIA-AA research framework proposes a purely biological definition of Alzheimer’s Disease (AD). This implies AD can be diagnosed based on biomarker abnormalities. While this brings opportunities, it also raises challenges.","PeriodicalId":501154,"journal":{"name":"medRxiv - Medical Ethics","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Medical Ethics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2021.09.16.21263690","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Introduction The NIA-AA research framework proposes a purely biological definition of Alzheimer’s Disease (AD). This implies AD can be diagnosed based on biomarker abnormalities. While this brings opportunities, it also raises challenges.
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