Association of effective circulating blood volume with sublingual RBC velocity and microvessel pressure difference in anesthetized individuals: A clinical investigation and computational fluid dynamics modeling
{"title":"Association of effective circulating blood volume with sublingual RBC velocity and microvessel pressure difference in anesthetized individuals: A clinical investigation and computational fluid dynamics modeling","authors":"Athanasios Chalkias, Michalis Xenos","doi":"10.1101/2022.05.09.22274826","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> Although changes in effective circulatory volume may affect microcirculatory red blood cell (RBC) velocity and oxygen extraction ratio, no systemic variable has been consistently associated with hemodynamic coherence. We therefore evaluated the association between mean circulatory filling pressure and microcirculatory perfusion and oxygenation.","PeriodicalId":501303,"journal":{"name":"medRxiv - Anesthesia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Anesthesia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2022.05.09.22274826","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Background Although changes in effective circulatory volume may affect microcirculatory red blood cell (RBC) velocity and oxygen extraction ratio, no systemic variable has been consistently associated with hemodynamic coherence. We therefore evaluated the association between mean circulatory filling pressure and microcirculatory perfusion and oxygenation.
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