{"title":"Research Progress in HIV and Mycobacterium tuberculosis Inhibitors Containing Sulfonamide Moiety","authors":"Christiana Abimbola Salubi","doi":"10.1155/2023/3601764","DOIUrl":null,"url":null,"abstract":"Numerous studies have reported significant results regarding the efficacy of sulfonamides against <i>Mycobacterium tuberculosis</i> and various HIV strains. This scientific paper provides an overview of the progress made over a decade of sulfonamides against HIV-1 and mycobacteria and its development against extremely drug-resistant (XDR) and multidrug-resistant strains. The reviewed study offers novel insights into the structural design and structure-activity relationship (SAR) of sulfonamides that are effective and less toxic in combating HIV, <i>Mycobacterium tuberculosis</i>, and multidrug resistance.","PeriodicalId":15348,"journal":{"name":"Journal of Chemistry","volume":"20 1","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1155/2023/3601764","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Numerous studies have reported significant results regarding the efficacy of sulfonamides against Mycobacterium tuberculosis and various HIV strains. This scientific paper provides an overview of the progress made over a decade of sulfonamides against HIV-1 and mycobacteria and its development against extremely drug-resistant (XDR) and multidrug-resistant strains. The reviewed study offers novel insights into the structural design and structure-activity relationship (SAR) of sulfonamides that are effective and less toxic in combating HIV, Mycobacterium tuberculosis, and multidrug resistance.
期刊介绍：
Journal of Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of chemistry.
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