S J Warrington, A Dawnay, A Johnston, S Saul, P Turner, H P Ferber
{"title":"Chlortenoxicam and renal function of normal human volunteers.","authors":"S J Warrington, A Dawnay, A Johnston, S Saul, P Turner, H P Ferber","doi":"10.1177/096032718900800110","DOIUrl":null,"url":null,"abstract":"new drug belonging to the oxicam class with a potency of about ten times that of piroxicam in standard animal models of inflammation and analgesia.2 Piroxicam causes nephrotoxicity in dogs, mice and rats, and there have been reports in man. 3,4 Nephrotoxicity was seen in one of six baboons receiving chlortenoxicam 0.5 mg kg-1 d-1 for 6 months, but no effects on renal function in man have yet been reported. The influence on renal function in man of chlor-","PeriodicalId":13194,"journal":{"name":"Human toxicology","volume":"8 1","pages":"53-4"},"PeriodicalIF":0.0000,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/096032718900800110","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Human toxicology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/096032718900800110","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
new drug belonging to the oxicam class with a potency of about ten times that of piroxicam in standard animal models of inflammation and analgesia.2 Piroxicam causes nephrotoxicity in dogs, mice and rats, and there have been reports in man. 3,4 Nephrotoxicity was seen in one of six baboons receiving chlortenoxicam 0.5 mg kg-1 d-1 for 6 months, but no effects on renal function in man have yet been reported. The influence on renal function in man of chlor-
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