High homocysteine levels as potential indicators of subacute combined degeneration of the spinal cord

Abstract

Background

Homocysteine (Hcy) is widely recognized as a significant risk factor for cardiovascular and cerebrovascular diseases. However, our research has uncovered a novel perspective, suggesting that elevated levels of Hcy could serve as an indicator for neurological diseases. This article presents a unique case of Subacute Combined Degeneration of the spinal cord(SCD), characterized by high homocysteine levels, yet normal vitamin B₁₂ and imaging results. This discovery could facilitate early detection and ensure timely referral of patients to specialized departments for further treatment.