High homocysteine levels as potential indicators of subacute combined degeneration of the spinal cord

Tingting Feng, Lizhen Wang, Fang Li, Fengjiao Li, Shunxian Wang, Ruijiao Zhou, Hongyu Lin, Ying Ma
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Abstract

Background

Homocysteine (Hcy) is widely recognized as a significant risk factor for cardiovascular and cerebrovascular diseases. However, our research has uncovered a novel perspective, suggesting that elevated levels of Hcy could serve as an indicator for neurological diseases. This article presents a unique case of Subacute Combined Degeneration of the spinal cord(SCD), characterized by high homocysteine levels, yet normal vitamin B12 and imaging results. This discovery could facilitate early detection and ensure timely referral of patients to specialized departments for further treatment.

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高同型半胱氨酸水平是脊髓亚急性联合变性的潜在指标
背景同型半胱氨酸(Hcy)被公认为是心脑血管疾病的重要危险因素。然而,我们的研究发现了一个新的视角,即 Hcy 水平升高可作为神经系统疾病的一个指标。本文介绍了一例独特的脊髓亚急性联合变性(SCD)病例,其特点是同型半胱氨酸水平高,但维生素 B12 和影像学结果正常。这一发现有助于早期发现并确保及时将患者转诊至专业部门接受进一步治疗。
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