Current status of Complementary and Alternative Medicine Interventions in the Management of Pancreatic Cancer – An Overview

IF 3.8 2区 医学 Q2 ONCOLOGY Current Treatment Options in Oncology Pub Date : 2023-12-11 DOI:10.1007/s11864-023-01146-4
Aleksandra Tarasiuk, Grzegorz Mirocha, Jakub Fichna
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Abstract

Pancreatic cancer (PC) remains the deadliest cancer worldwide. Most patients are diagnosed at the advanced or metastatic stage, leading to a poor prognosis. Awareness of the limitations of current therapy and accompanying pain, depression, malnutrition, and side effects of chemoradiotherapy may lead patients and physicians towards complementary and alternative medicine (CAM). CAM refers to a diverse set of medical and healthcare practices, products, and systems that are not part of conventional Western medicine. Despite the low-quality evidence supporting the efficacy of these methods, they remain appealing due to patients' beliefs, fear of death, and the slow development of conventional therapy. Hence, the possibility of using natural products for pancreatic cancer is increasing. CAM options such as: medical cannabis, plants, fungi, herbal formulas, and injections, which originate primarily from traditional Chinese or Japanese medicine i.e. Curcuma longa, Panax ginseng, Poria cocos, Hochuekkito, Juzentaihoto, and Rikkunshito, Shi-quan-da-bu-tang/TJ-48, Huang-qin-tang, Shuangbai San, Wen Jing Zhi Tong Fang, Xiang-Sha-Liu-jun-zi-tang, Aidi injection, Brucea javanica oil emulsion/Yadanziyouru injection, Compound Kushen injection, Huachansu injection, Kangai injection and Kanglaite injections are becoming promising candidates for the management of pancreatic cancer. The abovementioned substances/medications are the most popular or potentially effective in PC treatment and consequently CAM-based adjuvant therapy through improving patients’ quality of life, might be a useful addition in the treatment of pancreatic cancer patients.

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辅助与替代医学干预治疗胰腺癌的现状 - 概述
胰腺癌(PC)仍然是全球致死率最高的癌症。大多数患者确诊时已是晚期或转移期,预后较差。意识到目前疗法的局限性以及伴随而来的疼痛、抑郁、营养不良和化疗放疗的副作用,可能会引导患者和医生转向补充和替代医学(CAM)。CAM 指的是不属于传统西医的各种医疗和保健方法、产品和系统。尽管支持这些方法疗效的证据质量不高,但由于患者的信仰、对死亡的恐惧以及传统疗法发展缓慢,这些方法仍然很有吸引力。因此,使用天然产品治疗胰腺癌的可能性越来越大。CAM 选项包括:医用大麻、植物、真菌、草药配方和注射剂,它们主要源自传统中药或日本药,即莪术、三七、茯苓、虎杖、朱砂薏苡仁、六君子、石泉大补汤/TJ-48、黄芩汤、双柏散、温经止痛通方、香砂六君子汤、艾迪注射液、鸦胆子油乳剂/鸦胆子油注射液、复方苦参注射液、华蟾素注射液、康爱注射液和康莱特注射液正在成为治疗胰腺癌的有效候选药物。上述物质/药物是治疗胰腺癌最常用或潜在有效的方法,因此,通过改善患者的生活质量,基于 CAM 的辅助疗法可能是治疗胰腺癌患者的有益补充。
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来源期刊
CiteScore
7.10
自引率
0.00%
发文量
113
审稿时长
>12 weeks
期刊介绍: This journal aims to review the most important, recently published treatment option advances in the field of oncology. By providing clear, insightful, balanced contributions by international experts, the journal intends to facilitate worldwide approaches to cancer treatment. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as endocrine tumors, lymphomas, neuro-oncology, and cancers of the breast, head and neck, lung, skin, gastrointestinal tract, and genitourinary region. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known oncologists, and an international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research.
期刊最新文献
Updates in Systemic Treatment of Hormone Receptor-Positive Early-Stage Breast Cancer. The Role of SIRT1 in Leukemia. Clinical Trial Data Review of the Combination FTD/TPI + Bevacizumab in the Treatment Landscape of Unresectable Metastatic Colorectal Cancer. Correction to: Treatment of Anemia in Lower-Risk Myelodysplastic Syndrome. Diagnosis and Treatment of Myxoid Liposarcoma.
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