Synthesis, Characterization and Biocompatibility of Cross-linked Dicarboxylic Acids from Waste Potato Peel Starch

IF 1 4区生物学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Applied Biochemistry and Microbiology Pub Date : 2023-12-10 DOI:10.1134/S0003683823060108

S. Paşa, N. Gürler, Ö. Erdoğan, O. Cevik

{"title":"Synthesis, Characterization and Biocompatibility of Cross-linked Dicarboxylic Acids from Waste Potato Peel Starch","authors":"S. Paşa, N. Gürler, Ö. Erdoğan, O. Cevik","doi":"10.1134/S0003683823060108","DOIUrl":null,"url":null,"abstract":"<p>People have become conscious about recycling or reusing many things they use in the 21st century because diminishing vital resources make it necessary, both personally and socially. The evaluation of waste is also critical in terms of national economies. In this study, starch dicarboxylic compounds were synthesized using waste potato peels (WPP) in the presence of sodium hypophosphite monohydrate as a catalyst for the formation of the ester cross-links. Adipic acid, succinic acid, and glutaric acid were employed with waste potato starch (WPS) to obtain cross-linked samples: WPS-A, WPS-S, and WPS-G, respectively. The obtained compounds were characterized by attenuated total reflectance Fourier transform infrared (FTIR-ATR), scanning electron microscopy with energy-dispersive X-ray analysis (SEM-EDX), X-ray diffraction (XRD), and their cytotoxicity properties were investigated. The biocompatibility of the obtained WPS-dicarboxylic acid compounds against NIH-3T3 and L929 murine fibroblast cells with MTT assay was determined. Studies have shown that these compounds do not harm healthy cells and are found to be bioavailable.</p>","PeriodicalId":466,"journal":{"name":"Applied Biochemistry and Microbiology","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Biochemistry and Microbiology","FirstCategoryId":"99","ListUrlMain":"https://link.springer.com/article/10.1134/S0003683823060108","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

People have become conscious about recycling or reusing many things they use in the 21st century because diminishing vital resources make it necessary, both personally and socially. The evaluation of waste is also critical in terms of national economies. In this study, starch dicarboxylic compounds were synthesized using waste potato peels (WPP) in the presence of sodium hypophosphite monohydrate as a catalyst for the formation of the ester cross-links. Adipic acid, succinic acid, and glutaric acid were employed with waste potato starch (WPS) to obtain cross-linked samples: WPS-A, WPS-S, and WPS-G, respectively. The obtained compounds were characterized by attenuated total reflectance Fourier transform infrared (FTIR-ATR), scanning electron microscopy with energy-dispersive X-ray analysis (SEM-EDX), X-ray diffraction (XRD), and their cytotoxicity properties were investigated. The biocompatibility of the obtained WPS-dicarboxylic acid compounds against NIH-3T3 and L929 murine fibroblast cells with MTT assay was determined. Studies have shown that these compounds do not harm healthy cells and are found to be bioavailable.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

从废弃马铃薯皮淀粉中提取的交联二羧酸的合成、表征和生物相容性

摘要在 21 世纪，人们开始有意识地回收或再利用他们使用的许多东西，因为日益减少的重要资源使回收或再利用成为个人和社会的必要之举。对废物的评估对国民经济也至关重要。在这项研究中，使用废弃马铃薯皮（WPP）合成了淀粉二羧酸化合物，并以一水次磷酸钠作为形成酯交联的催化剂。将己二酸、琥珀酸和戊二酸与废弃马铃薯淀粉（WPS）一起使用以获得交联样品：分别为 WPS-A、WPS-S 和 WPS-G。通过衰减全反射傅立叶变换红外光谱（FTIR-ATR）、扫描电子显微镜与能量色散 X 射线分析（SEM-EDX）、X 射线衍射（XRD）对得到的化合物进行了表征，并研究了它们的细胞毒性特性。利用 MTT 试验测定了所获得的 WPS 二羧酸化合物对 NIH-3T3 和 L929 小鼠成纤维细胞的生物相容性。研究表明，这些化合物不会伤害健康细胞，而且具有生物可利用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Applied Biochemistry and Microbiology 生物-生物工程与应用微生物

CiteScore

1.70

自引率

12.50%

发文量

审稿时长

6-12 weeks

期刊介绍： Applied Biochemistry and Microbiology is an international peer reviewed journal that publishes original articles on biochemistry and microbiology that have or may have practical applications. The studies include: enzymes and mechanisms of enzymatic reactions, biosynthesis of low and high molecular physiologically active compounds; the studies of their structure and properties; biogenesis and pathways of their regulation; metabolism of producers of biologically active compounds, biocatalysis in organic synthesis, applied genetics of microorganisms, applied enzymology; protein and metabolic engineering, biochemical bases of phytoimmunity, applied aspects of biochemical and immunochemical analysis; biodegradation of xenobiotics; biosensors; biomedical research (without clinical studies). Along with experimental works, the journal publishes descriptions of novel research techniques and reviews on selected topics.