Senecavirus a induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185

IF 14.6 1区 生物学 Q1 CELL BIOLOGY Autophagy Pub Date : 2023-12-12 DOI:10.1080/15548627.2023.2293442
Meirong Chen, Xin Zhang, Fanshu Kong, Peng Gao, Xinna Ge, Lei Zhou, Jun Han, Xin Guo, Yongning Zhang, Hanchun Yang
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Abstract

Senecavirus A (SVA) is a newly emerging picornavirus associated with swine vesicular lesions and neonatal mortality, threatening the global pig industry. Despite sustained efforts, the molecular me...
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森纳卡病毒 a 通过 2C 蛋白与 RNF185 催化的 K27 链接泛素化 TUFM 的直接相互作用,诱导有丝分裂以促进自我复制
塞内卡病毒 A(SVA)是一种新出现的皮卡病毒,与猪水泡病和新生儿死亡有关,威胁着全球养猪业。尽管做出了不懈的努力,但分子生物学...
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来源期刊
Autophagy
Autophagy 生物-细胞生物学
CiteScore
21.30
自引率
2.30%
发文量
277
审稿时长
1 months
期刊介绍: Autophagy is a peer-reviewed journal that publishes research on autophagic processes, including the lysosome/vacuole dependent degradation of intracellular material. It aims to be the premier journal in the field and covers various connections between autophagy and human health and disease, such as cancer, neurodegeneration, aging, diabetes, myopathies, and heart disease. Autophagy is interested in all experimental systems, from yeast to human. Suggestions for specialized topics are welcome. The journal accepts the following types of articles: Original research, Reviews, Technical papers, Brief Reports, Addenda, Letters to the Editor, Commentaries and Views, and Articles on science and art. Autophagy is abstracted/indexed in Adis International Ltd (Reactions Weekly), EBSCOhost (Biological Abstracts), Elsevier BV (EMBASE and Scopus), PubMed, Biological Abstracts, Science Citation Index Expanded, Web of Science, and MEDLINE.
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