Mengli Xu, Weifang Zhou, Yuewen Su, Meng Cao, Yuqin Li
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Abstract
Aim: To investigate the expression and clinical significance of IL-17A and IL-22 in the plasma of children with infectious mononucleosis complicated with liver damage caused by Epstein–Barr virus. Method: Peripheral plasma was collected from 64 children with IM. We compared IL-17A, IL-22, the clinical data and laboratory examination indicators between liver damage and non-liver damage groups. Results: We found that the levels of IL-17A and IL-22 were higher in the liver damage group and positively correlated with liver function indicators. CD4+/CD8+ was lower in the liver damage group. Conclusion: The study provides valuable insights into the clinical significance of IL-17A and IL-22 in children with IM complicated with liver damage caused by EBV.
期刊介绍：
Future Virology is a peer-reviewed journal that delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this ever-expanding area of research. It is an interdisciplinary forum for all scientists working in the field today.
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