Expression and significance of IL-17A and IL-22 in children with infectious mononucleosis complicated with liver damage

IF 2.1 4区 医学 Q3 VIROLOGY Future Virology Pub Date : 2023-12-04 DOI:10.2217/fvl-2023-0104
Mengli Xu, Weifang Zhou, Yuewen Su, Meng Cao, Yuqin Li
{"title":"Expression and significance of IL-17A and IL-22 in children with infectious mononucleosis complicated with liver damage","authors":"Mengli Xu, Weifang Zhou, Yuewen Su, Meng Cao, Yuqin Li","doi":"10.2217/fvl-2023-0104","DOIUrl":null,"url":null,"abstract":"Aim: To investigate the expression and clinical significance of IL-17A and IL-22 in the plasma of children with infectious mononucleosis complicated with liver damage caused by Epstein–Barr virus. Method: Peripheral plasma was collected from 64 children with IM. We compared IL-17A, IL-22, the clinical data and laboratory examination indicators between liver damage and non-liver damage groups. Results: We found that the levels of IL-17A and IL-22 were higher in the liver damage group and positively correlated with liver function indicators. CD4+/CD8+ was lower in the liver damage group. Conclusion: The study provides valuable insights into the clinical significance of IL-17A and IL-22 in children with IM complicated with liver damage caused by EBV.","PeriodicalId":12505,"journal":{"name":"Future Virology","volume":"14 3","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2023-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future Virology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2217/fvl-2023-0104","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VIROLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Aim: To investigate the expression and clinical significance of IL-17A and IL-22 in the plasma of children with infectious mononucleosis complicated with liver damage caused by Epstein–Barr virus. Method: Peripheral plasma was collected from 64 children with IM. We compared IL-17A, IL-22, the clinical data and laboratory examination indicators between liver damage and non-liver damage groups. Results: We found that the levels of IL-17A and IL-22 were higher in the liver damage group and positively correlated with liver function indicators. CD4+/CD8+ was lower in the liver damage group. Conclusion: The study provides valuable insights into the clinical significance of IL-17A and IL-22 in children with IM complicated with liver damage caused by EBV.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
感染性单核细胞增多症并发肝损伤儿童中 IL-17A 和 IL-22 的表达及其意义
目的:探讨传染性单核细胞增多症合并eb病毒肝损害患儿血浆中IL-17A、IL-22的表达及临床意义。方法:收集64例小儿外周血浆。比较肝损害组与非肝损害组的IL-17A、IL-22、临床资料及实验室检查指标。结果:我们发现肝损害组IL-17A、IL-22水平较高,且与肝功能指标呈正相关。肝损伤组CD4+/CD8+较低。结论:IL-17A和IL-22在IM合并EBV肝损害患儿中的临床意义具有重要意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Future Virology
Future Virology 医学-病毒学
CiteScore
4.00
自引率
3.20%
发文量
84
审稿时长
6-12 weeks
期刊介绍: Future Virology is a peer-reviewed journal that delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this ever-expanding area of research. It is an interdisciplinary forum for all scientists working in the field today.
期刊最新文献
Trends and perspectives in tuberculosis and HIV co-infection studies over the past three decades Human RSVA-ON1, the only genotype present during 2019–2020 winter season in Riyadh, Saudi Arabia: a retrospective study Rosmarinic acid inhibits Rift Valley fever virus: in vitro, computational and analytical studies Plain language summary of the efficacy and safety of bepirovirsen in patients with chronic hepatitis B infection Expression and significance of IL-17A and IL-22 in children with infectious mononucleosis complicated with liver damage
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1