Infective Endocarditis in the Colombian Caribbean Region: Clinical Profile, Microbiological Insights, and Risk Factors for Mortality

Gabriela Solarte Bastidas
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Abstract

Background: Infective endocarditis (IE) is defined as the infectious and inflammatory process of the heart’s internal structures. It can be caused by a broad group of bacteria and, rarely, fungi, with potentially life-threatening consequences. Objective: To profile bacterial resistance and identify mortality risk factors in IE patients. Methods: This cross-sectional study included clinically diagnosed IE patients. Sociodemographic, comorbidity, clinical, and microbiological data were recorded. Descriptive analyses, Chi-Square/Fisher’s exact tests, and Student’s t-tests examined variables in relation to IE outcomes (survival vs. mortality). Multivariate logistic regression calculated odds ratios and confidence intervals.
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哥伦比亚加勒比地区的感染性心内膜炎:临床概况、微生物学见解和死亡风险因素
背景:感染性心内膜炎(IE)被定义为心脏内部结构的感染和炎症过程。它可以由广泛的细菌引起,很少由真菌引起,具有潜在的危及生命的后果。目的:了解IE患者的细菌耐药性并确定其死亡危险因素。方法:本横断面研究纳入临床诊断的IE患者。记录社会人口学、合并症、临床和微生物学数据。描述性分析、卡方/费雪精确检验和学生t检验检验了与IE结果(生存率与死亡率)相关的变量。多元逻辑回归计算优势比和置信区间。
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