Neurophysiological approach to the assessment of spinal cord function in kyphotic spinal deformity

I. Ilyasevich, E. Soshnikova, D. K. Tesakov, V. A. Kulchitsky, I. S. Khomushka
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Abstract

The results of a comprehensive (clinical-radiological and neurophysiological) study performed in two clinical groups of patients (n = 64) with kyphotic spinal deformity of II–IV degree of severity of the thoracic and lumbar spine of various etiologies were analysed. With the progression of kyphotic spine deformity, the spinal cord (SC) located inside the spinal canal becomes involved in the pathological process. This period of dysfunction is preceded by a state of latent SM changes that are not detected clinically (prodromal period). The presence of neurological disorders is considered as a factor of increased risk of intra- and postoperative complications in the surgical treatment of kyphosis. Based on the registration and analysis of the parameters of somatosensory evoked potentials and motor responses during transcranial magnetic stimulation, electrophysiological signs of sensorimotor insufficiency of the SС nerve tracts were revealed, which correlate with the kyphotic arch value. The established electrophysiological criteria allow to verify the level of conductive lesion at the level of thoracic and lumbar SC segments, to determine its severity, to monitor recovery processes and to predict the functional outcome.
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用神经生理学方法评估畸形脊柱的脊髓功能
对两组不同病因的胸腰椎II-IV级脊柱后凸畸形患者(n = 64)进行综合(临床-放射学和神经生理学)研究分析。随着脊柱后凸畸形的进展,位于椎管内的脊髓(SC)参与了病理过程。这段功能障碍期之前是一种未被临床检测到的潜在SM变化状态(前驱期)。神经系统疾病的存在被认为是后凸手术治疗中增加术中和术后并发症风险的一个因素。通过对经颅磁刺激过程中体感诱发电位和运动反应参数的登记和分析,揭示了SС神经束感觉运动功能不全的电生理特征,这些电生理特征与后凸弓值相关。已建立的电生理标准可以验证胸椎和腰椎SC节段的传导损伤水平,确定其严重程度,监测恢复过程并预测功能结果。
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35
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