Mechanisms of long COVID: An updated review

Yan Liu , Xiaoying Gu , Haibo Li , Hui Zhang , Jiuyang Xu
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引用次数: 0

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has been ongoing for more than 3 years, with an enormous impact on global health and economies. In some patients, symptoms and signs may remain after recovery from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which cannot be explained by an alternate diagnosis; this condition has been defined as long COVID. Long COVID may exist in patients with both mild and severe disease and is prevalent after infection with different SARS-CoV-2 variants. The most common symptoms include fatigue, dyspnea, and other symptoms involving multiple organs. Vaccination results in lower rates of long COVID. To date, the mechanisms of long COVID remain unclear. In this narrative review, we summarized the clinical presentations and current evidence regarding the pathogenesis of long COVID.

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长 COVID 的机制:最新综述
冠状病毒病 2019(COVID-19)大流行已持续 3 年多,对全球健康和经济造成了巨大影响。一些患者在从严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)感染中恢复后,症状和体征可能仍然存在,无法用其他诊断来解释;这种情况被定义为长 COVID。轻度和重度患者都可能出现长COVID,感染不同的SARS-CoV-2变体后也会出现长COVID。最常见的症状包括疲劳、呼吸困难和其他涉及多个器官的症状。接种疫苗可降低长COVID的发病率。迄今为止,长效 COVID 的发病机制仍不清楚。在这篇叙述性综述中,我们总结了长COVID的临床表现和目前有关其发病机制的证据。
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来源期刊
Chinese medical journal pulmonary and critical care medicine
Chinese medical journal pulmonary and critical care medicine Critical Care and Intensive Care Medicine, Infectious Diseases, Pulmonary and Respiratory Medicine
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