Fabrication and in vitro characterization of delafloxacin-laden electrosprayed hydroxypropyl cellulose nanoparticulated solid dispersions for enhanced aqueous solubility and release rate of the drug

IF 2.5 4区 医学 Q4 MATERIALS SCIENCE, BIOMATERIALS International Journal of Polymeric Materials and Polymeric Biomaterials Pub Date : 2023-12-11 DOI:10.1080/00914037.2023.2289521
Muhammad Ramzan, Abid Mehmood Yousaf, Ikram Ullah Khan
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Abstract

With the aim of fabricating and characterizing an optimized drug delivery system (DDS) for an effective administration of poorly water-soluble delafloxacin (DFX) via the oral route, several formula...
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用于提高药物水溶性和释放率的含羟丙基纤维素的德拉氧氟沙星电喷雾纳米颗粒固体分散体的制备和体外表征
为了制备和表征一种优化的药物传递系统(DDS),通过口服途径有效地给药低水溶性德拉沙星(DFX),几种配方…
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来源期刊
International Journal of Polymeric Materials and Polymeric Biomaterials
International Journal of Polymeric Materials and Polymeric Biomaterials Chemical Engineering-General Chemical Engineering
CiteScore
8.00
自引率
3.10%
发文量
97
审稿时长
3.3 months
期刊介绍: International Journal of Polymeric Materials and Polymeric Biomaterials is the official publication of the International Society for Biomedical Polymers and Polymeric Biomaterials (ISBPPB). This journal provides a forum for the publication of peer-reviewed, English language articles and select reviews on all aspects of polymeric materials and biomedical polymers. Being interdisciplinary in nature, this journal publishes extensive contributions in the areas of encapsulation and controlled release technologies to address innovation needs as well.
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