Onconephrology: mitigation of renal injury in chemotherapy administration.

IF 2.2 3区 医学 Q3 PERIPHERAL VASCULAR DISEASE Current Opinion in Nephrology and Hypertension Pub Date : 2023-12-15 DOI:10.1097/mnh.0000000000000960
Umut Selamet, Rebecca S Ahdoot, Reed Salasnek, Lama Abdelnour, Ramy M Hanna
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Abstract

Onconephrology was first coined as a name for the intersection of cancer medicine and nephrology in the early 2010s. It was recognized then that beyond and understanding of kidney physiology, a new generation of nephrologists skilled in both molecular biology and precision medicine were needed to deal with the challenges of emerging cancer therapies. Stem cell transplants, biologic agents, adjuvants blocking basic cellular signaling pathways, immunotherapy were found to promote novel anticancer outcomes, but also to pose new risks to the kidneys. The field rapidly overlapped with emerging expertise in vascular glomerular disease, glomerular disease, and the same biologic agents now applied to auto immune systemic and kidney diseases.
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肿瘤肾脏病学:减轻化疗对肾脏的损伤。
肿瘤肾脏病学最早是在 2010 年代初作为癌症医学和肾脏病学的交叉学科而出现的。当时人们认识到,除了了解肾脏生理学,还需要新一代精通分子生物学和精准医学的肾病学家来应对新兴癌症疗法的挑战。人们发现,干细胞移植、生物制剂、阻断基本细胞信号通路的辅助剂和免疫疗法可促进新的抗癌效果,但也会对肾脏造成新的风险。这一领域迅速与血管性肾小球疾病、肾小球疾病以及现在用于自身免疫系统和肾脏疾病的相同生物制剂的新兴专业知识重叠。
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来源期刊
Current Opinion in Nephrology and Hypertension
Current Opinion in Nephrology and Hypertension 医学-泌尿学与肾脏学
CiteScore
5.70
自引率
6.20%
发文量
132
审稿时长
6-12 weeks
期刊介绍: A reader-friendly resource, Current Opinion in Nephrology and Hypertension provides an up-to-date account of the most important advances in the field of nephrology and hypertension. Each issue contains either two or three sections delivering a diverse and comprehensive coverage of all the key issues, including pathophysiology of hypertension, circulation and hemodynamics, and clinical nephrology. Current Opinion in Nephrology and Hypertension is an indispensable journal for the busy clinician, researcher or student.
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