Nanomaterial-assisted wearable glucose biosensors for noninvasive real-time monitoring: Pioneering point-of-care and beyond

IF 9.9 2区 材料科学 Q1 Engineering Nano Materials Science Pub Date : 2024-06-01 DOI:10.1016/j.nanoms.2023.11.009
Moein Safarkhani , Abdullah Aldhaher , Golnaz Heidari , Ehsan Nazarzadeh Zare , Majid Ebrahimi Warkiani , Omid Akhavan , YunSuk Huh , Navid Rabiee
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Abstract

This review explores glucose monitoring and management strategies, emphasizing the need for reliable and user-friendly wearable sensors that are the next generation of sensors for continuous glucose detection. In addition, examines key strategies for designing glucose sensors that are multi-functional, reliable, and cost-effective in a variety of contexts. The unique features of effective diabetes management technology are highlighted, with a focus on using nano/biosensor devices that can quickly and accurately detect glucose levels in the blood, improving patient treatment and control of potential diabetes-related infections. The potential of next-generation wearable and touch-sensitive nano biomedical sensor engineering designs for providing full control in assessing implantable, continuous glucose monitoring is also explored. The challenges of standardizing drug or insulin delivery doses, low-cost, real-time detection of increased blood sugar levels in diabetics, and early digital health awareness controls for the adverse effects of injectable medication are identified as unmet needs. Also, the market for biosensors is expected to expand significantly due to the rising need for portable diagnostic equipment and an ever-increasing diabetic population. The paper concludes by emphasizing the need for further research and development of glucose biosensors to meet the stringent requirements for sensitivity and specificity imposed by clinical diagnostics while being cost-effective, stable, and durable.

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用于无创实时监测的纳米材料辅助可穿戴葡萄糖生物传感器:开拓护理点及其他领域
这篇综述探讨了葡萄糖监测和管理策略,强调需要可靠、用户友好的可穿戴式传感器作为下一代连续葡萄糖检测传感器。此外,还探讨了在各种情况下设计多功能、可靠和具有成本效益的葡萄糖传感器的关键策略。重点介绍了有效的糖尿病管理技术的独特之处,包括使用纳米/生物传感器设备,快速准确地检测血液中的葡萄糖水平,改善患者治疗,控制潜在的糖尿病相关感染。此外,还探讨了下一代可穿戴和触敏纳米生物医学传感器工程设计在评估植入式连续葡萄糖监测中提供全面控制的潜力。标准化药物或胰岛素给药剂量、低成本、实时检测糖尿病患者血糖水平升高以及针对注射药物不良反应的早期数字健康意识控制等挑战被认为是尚未满足的需求。此外,由于对便携式诊断设备的需求不断增长以及糖尿病患者人数不断增加,预计生物传感器市场将显著扩大。本文最后强调,有必要进一步研究和开发葡萄糖生物传感器,以满足临床诊断对灵敏度和特异性的严格要求,同时保证其成本效益、稳定性和耐用性。
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来源期刊
Nano Materials Science
Nano Materials Science Engineering-Mechanics of Materials
CiteScore
20.90
自引率
3.00%
发文量
294
审稿时长
9 weeks
期刊介绍: Nano Materials Science (NMS) is an international and interdisciplinary, open access, scholarly journal. NMS publishes peer-reviewed original articles and reviews on nanoscale material science and nanometer devices, with topics encompassing preparation and processing; high-throughput characterization; material performance evaluation and application of material characteristics such as the microstructure and properties of one-dimensional, two-dimensional, and three-dimensional nanostructured and nanofunctional materials; design, preparation, and processing techniques; and performance evaluation technology and nanometer device applications.
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