STAT4 Phosphorylation of T-helper Cells predicts surgical outcomes in Refractory Chronic Rhinosinusitis

Michael R. Abidin, Oral Alpan, Matthew Plassmeyer, Lina Kozhaya, Denise Loizou, Mikail Dogan, Zachary Upchurch, Nathan P Manes, Aleksandra Nita-Lazar, Derya Unutmaz, Søren Ulrik Sønder
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Abstract

Objective: Chronic rhinosinusitis (CRS) impacts an estimated 5% to 15% of people worldwide, incurring significant economic healthcare burden. There is a urgent need for the discovery of predictive biomarkers to improve treatment strategies and outcomes for CRS patients.
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T 辅助细胞的 STAT4 磷酸化可预测难治性慢性鼻炎的手术效果
目的:据估计,慢性鼻炎(CRS)影响着全球 5%至 15%的人口,给医疗保健带来了巨大的经济负担。目前迫切需要发现预测性生物标志物,以改善 CRS 患者的治疗策略和疗效。
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