Estimation of ethanol and methanol exposure through jarred fruit purees.

IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Annali dell'Istituto superiore di sanita Pub Date : 2023-10-01 DOI:10.4415/ANN_23_04_04
Mukaddes Gürler, Belgin Bayram
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Abstract

Introduction: Chemicals in foods enter the human body from early life likely posing chronic toxic health risks in the future. This study aimed to estimate the exposure to ethanol and methanol in children consuming an acceptable daily amount of fruit purees.

Methods: Different fruit purees were purchased and measured for methanol and ethanol by using HS-GC. The exposure dose of these alcohols was calculated based on a consumption of 125-250 g of fruit purees in children weighing 7, 12 and 16 kg.

Results: The highest methanol was found in carrot-apple puree (29.07 mg/dL) and ethanol in peach-banana puree (42.07 mg/dL). Daily methanol exposure was estimated between 4.54 and 6.06, and ethanol between 6.57 and 8.76 mg/kg bw.

Conclusions: Our results show higher exposure doses of methanol and ethanol than allowable ones (methanol 2 and ethanol 6 mg/kg/day) in children consuming fruit purees. This should be handled as a public health risk and further comprehensive studies should be enrolled on the chronic toxic effects of food-derived alcohols. Besides, food-derived exposure to toxic chemicals from early life should be more questioned by physicians (in assessing chronic diseases), and related authorities should establish a sustainable, safe, and healthy food production policy.

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估算罐装果泥中乙醇和甲醇的暴露量。
导言:食品中的化学物质从幼年开始就进入人体,很可能在未来造成慢性毒性健康风险。本研究旨在估算每天食用可接受量果泥的儿童的乙醇和甲醇暴露量:方法:购买不同的果泥,使用 HS-GC 测量甲醇和乙醇含量。根据体重为 7、12 和 16 公斤的儿童食用 125-250 克果泥的量来计算这些酒精的暴露剂量:结果:胡萝卜苹果泥中的甲醇含量最高(29.07 毫克/分升),桃香蕉泥中的乙醇含量最高(42.07 毫克/分升)。据估计,每日甲醇摄入量为 4.54 至 6.06 毫克/千克体重,乙醇摄入量为 6.57 至 8.76 毫克/千克体重:我们的研究结果表明,食用果泥的儿童接触甲醇和乙醇的剂量高于允许剂量(甲醇 2 毫克/千克/天,乙醇 6 毫克/千克/天)。这应作为公共卫生风险加以处理,并应就食物衍生酒精的慢性毒性影响开展进一步的综合研究。此外,医生(在评估慢性疾病时)应更多地质疑从幼年开始接触有毒化学物质的食物来源,相关部门应制定可持续、安全和健康的食品生产政策。
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来源期刊
Annali dell'Istituto superiore di sanita
Annali dell'Istituto superiore di sanita PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
3.80
自引率
4.80%
发文量
65
审稿时长
>12 weeks
期刊介绍: Annali dell’Istituto Superiore di Sanità is a peer reviewed quarterly science journal which publishes research articles in biomedicine, translational research and in many other disciplines of the health sciences. The journal includes the following material: original articles, reviews, commentaries, editorials, brief and technical notes, book reviews. The publication of Monographic Sections has been discontinued. In case you wish to present a small number of coordinated contributions on specific themes concerning priorities in public health, please contact the Editorial office. The journal is in English.
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