The dementia severity rating scale: A potential community screening tool for dementia in low- and middle-income countries.

Dementia (London, England) Pub Date : 2024-04-01 Epub Date: 2023-12-14 DOI:10.1177/14713012231186837
Yuda Turana, Nicolas Farina, Imelda Theresia, Fasihah Irfani Fitri, Ika Suswanti, Roxanne Jacobs, Marguerite Schneider, Tara Puspitarini Sani, Adelina Comas-Herrera, Emiliano Albanese, Ishtar Govia, Cleusa P Ferri, Martin Knapp, Sube Banerjee
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Abstract

Background: The Dementia Severity Rating Scale (DSRS) is an informant report, dementia staging tool that is quick to administer and has previous been shown to differentiate between people with dementia and healthy controls. However, it is not clear how accurate the tool is screening against diagnostic criteria in middle-income settings.

Methods: Embedded within the STRiDE programme, older adults (aged ≥65 years) and their informants were randomly recruited from four sites across Indonesia and South Africa. All informants were asked to complete DSRS. We report the tool's psychometric properties and accuracy against the 10/66 short diagnostic algorithm.

Results: Between September and December 2021, data was collected from 2110 older adults in Indonesia and 408 in South Africa. Overall, the DSRS scores significantly differed between those with and without dementia, as identified on the 10/66 short algorithm (p < .05). The difference between groups remained significant after controlling for key factors related to older adult and informant demographics. A score >2 on the DSRS had the greatest agreement with the 10/66 short algorithm and had excellent discriminative properties in both Indonesia (Area Under Curve (AUC) = .75, 95% CIs = .72-.77) and South Africa (AUC = .82, 95% CIs = .76-.88).

Conclusions: The DSRS has potential as a screening tool for dementia in middle-income countries, with high sensitivity and specificity against a standardized diagnostic algorithm.

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痴呆症严重程度量表:中低收入国家痴呆症的潜在社区筛查工具。
背景:痴呆症严重程度评定量表(DSRS)是一种由信息提供者报告的痴呆症分期工具,该工具操作简便,以前曾被证明可以区分痴呆症患者和健康对照者。然而,目前还不清楚该工具在中等收入环境中对照诊断标准进行筛查的准确性:在 STRiDE 计划中,从印度尼西亚和南非的四个地点随机招募老年人(年龄≥65 岁)及其信息提供者。所有信息提供者都被要求完成 DSRS。我们报告了该工具的心理测量特性以及与 10/66 简易诊断算法对照的准确性:2021 年 9 月至 12 月期间,我们收集了印度尼西亚 2110 名老年人和南非 408 名老年人的数据。总体而言,根据 10/66 简易算法确定的痴呆症患者和非痴呆症患者的 DSRS 分数有显著差异(p < .05)。在控制了与老年人和信息提供者人口统计学相关的关键因素后,组间差异仍然显著。在印度尼西亚(Area Under Curve (AUC) = .75,95% CIs = .72-.77)和南非(AUC = .82,95% CIs = .76-.88),DSRS得分大于2分与10/66简易算法的一致性最高,并具有极佳的鉴别特性:DSRS具有在中等收入国家作为痴呆症筛查工具的潜力,与标准化诊断算法相比,具有较高的灵敏度和特异性。
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