Evidence on the use of alternative substances and therapies in hypertension

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 DOI:10.1016/j.hipert.2023.11.001

E. Martín-Riobóo , M. Turégano-Yedro , J.R. Banegas

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Abstract

Objective

Review of some of the best-known biological and non-biological complementary/alternative therapies/medicines (CAM) and their relationship with blood pressure (BP) and hypertension (HT).

Search strategy

Narrative review assessing a recent series of systematic reviews, meta-analyses, and clinical trials published in recent years, focusing on the effects of CAM on BP and HT.

Selection of studies

We searched EMBASE, MEDLINE, Cochrane Library and Google Scholar, obtaining a total of 4336 articles, finally limiting the search to 181 after applying filters.

Synthesis of results

Some studies on biological therapies show some usefulness in BP reduction with an adequate benefit–risk balance, although there is a scarcity of high-quality trials that support these results. Some mind-body therapies have shown hypothetical benefit; in contrast, others lack robust evidence.

Conclusions

Although some therapies present a reasonable risk–benefit ratio, they should in no case replace pharmacological treatment when indicated.

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使用替代物质和疗法治疗高血压的证据。

摘要综述一些最著名的生物和非生物补充/替代疗法/药物（CAM）及其与血压（BP）和高血压（HT）的关系：叙述性综述：评估近年来发表的一系列系统综述、荟萃分析和临床试验，重点关注 CAM 对血压和高血压的影响：我们检索了 EMBASE、MEDLINE、Cochrane Library 和 Google Scholar，共获得 4336 篇文章，经过筛选，最终将搜索范围限制在 181 篇：一些关于生物疗法的研究表明，生物疗法在降低血压方面有一定作用，且能充分平衡收益与风险，但支持这些结果的高质量试验很少。一些身心疗法显示出假定的益处；相比之下，其他疗法则缺乏有力的证据：结论：尽管某些疗法具有合理的风险收益比，但在任何情况下都不应取代药物治疗。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.