[Effects of low-frequency ultrasound on tumors cells in experimental animals].

Grudnaia khirurgiia (Moscow, Russia) Pub Date : 1989-05-01
Iu V Biriukov, G F Sheremet'eva, V S Moiseev, G V Kirdan, G M Khodzhimatov
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Abstract

The effect of low-frequency ultrasound was studied in different conditions in 197 in vitro experiments according to the histological form of the tumor. It was found that ultrasound with a frequency of 26.6--40.5 kHz, intensity of 2--8 Wt/cm2, and fluctuation amplitude of the end of the smooth cylindrical instrument-wave guide of 60--80 mcm caused destruction of the cells of malignant tumors of humans, whatever the histological form. Experiments with transplanted tumors--Zaidel's ascitic hematoma and sarcoma M-l of rats (202 rats) showed that after transplantation of a tumor cell suspension exposed to sonic waves for 5--7 minutes a tumor does not develop in highly susceptible experimental animals.

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[低频超声对实验动物肿瘤细胞的影响]。
根据肿瘤的组织学形态,在197例体外实验中研究了不同条件下低频超声的作用。研究发现,频率为26.6—40.5 kHz,强度为2—8 Wt/cm2,仪器光滑圆柱形波导末端波动幅度为60—80 mcm的超声可破坏人类恶性肿瘤细胞,无论其组织学形式如何。移植肿瘤的实验-大鼠(202只大鼠)的Zaidel腹水血肿和肉瘤m - 1表明,在高度敏感的实验动物中,将肿瘤细胞悬液暴露在声波中5- 7分钟后,肿瘤不会发展。
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