Iu V Biriukov, G F Sheremet'eva, V S Moiseev, G V Kirdan, G M Khodzhimatov
{"title":"[Effects of low-frequency ultrasound on tumors cells in experimental animals].","authors":"Iu V Biriukov, G F Sheremet'eva, V S Moiseev, G V Kirdan, G M Khodzhimatov","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The effect of low-frequency ultrasound was studied in different conditions in 197 in vitro experiments according to the histological form of the tumor. It was found that ultrasound with a frequency of 26.6--40.5 kHz, intensity of 2--8 Wt/cm2, and fluctuation amplitude of the end of the smooth cylindrical instrument-wave guide of 60--80 mcm caused destruction of the cells of malignant tumors of humans, whatever the histological form. Experiments with transplanted tumors--Zaidel's ascitic hematoma and sarcoma M-l of rats (202 rats) showed that after transplantation of a tumor cell suspension exposed to sonic waves for 5--7 minutes a tumor does not develop in highly susceptible experimental animals.</p>","PeriodicalId":73184,"journal":{"name":"Grudnaia khirurgiia (Moscow, Russia)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1989-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Grudnaia khirurgiia (Moscow, Russia)","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The effect of low-frequency ultrasound was studied in different conditions in 197 in vitro experiments according to the histological form of the tumor. It was found that ultrasound with a frequency of 26.6--40.5 kHz, intensity of 2--8 Wt/cm2, and fluctuation amplitude of the end of the smooth cylindrical instrument-wave guide of 60--80 mcm caused destruction of the cells of malignant tumors of humans, whatever the histological form. Experiments with transplanted tumors--Zaidel's ascitic hematoma and sarcoma M-l of rats (202 rats) showed that after transplantation of a tumor cell suspension exposed to sonic waves for 5--7 minutes a tumor does not develop in highly susceptible experimental animals.
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