Resolution of the Council of Experts “Results of a multicenter, randomized, double-blind, placebo-controlled study of ARTNEO in patients with stage II–III primary knee osteoarthritis”

A. Lila, L. Alekseeva, I. Belyaeva, I. B. Vinogradova, N. A. Demidova, O. Kalyuzhin, I. I. Nesterovich, V. Sorotskaya, L. Y. Shirokova, S. Yakupova
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Abstract

On August 31,2023 in V.A. Nasonova Research Institute of Rheumatology a meeting of the Expert Council was held at which the principal investigators and co-investigators of the ARTNEO-2021 protocol "Multicenter randomized double-blind, placebo-controlled study of ARTNEO in patients with stage II-III primary knee osteoarthritis" was held. A consensus position was developed on the possibility and feasibility of using a combination of undenatured (native) type II collagen, methylsulfonylmethane, boswellic acids, vitamins C and D (ARTNEO complex) in clinical practice. Based on the results of the study, the use of the ARTNEO complex can be recommended as part of a complex therapy for patients with osteoarthritis as a course treatment with total duration up to 6 months. The results of the study can only be interpreted in relation to ARTNEO and cannot be transferred to preparations with a different composition.
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专家委员会决议 "针对 II-III 期原发性膝骨关节炎患者的 ARTNEO 多中心、随机、双盲、安慰剂对照研究结果"
2023年8月31日,在瓦-阿-纳索诺娃(V.A. Nasonova)风湿病学研究所召开了专家委员会会议,ARTNEO-2021方案 "ARTNEO对II-III期原发性膝骨关节炎患者的多中心随机双盲安慰剂对照研究 "的主要研究人员和共同研究人员参加了会议。会议就在临床实践中使用未变性(原生)II型胶原蛋白、甲磺酰甲烷、乳香酸、维生素C和维生素D复合物(ARTNEO复合物)的可能性和可行性达成了共识。根据研究结果,可以建议骨关节炎患者将 ARTNEO 复合物作为复合疗法的一部分,作为疗程治疗,总疗程不超过 6 个月。研究结果只能针对 ARTNEO 进行解释,不能用于不同成分的制剂。
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