{"title":"Unlocking the significance of CD226 in cancer","authors":"Weili Sun","doi":"10.46439/signaling.2.021","DOIUrl":null,"url":null,"abstract":"Cancer remains a significant global health challenge, with researchers continually striving to unravel the complexities of its development and progression. In recent years, CD226, also known as DNAM-1, has emerged as a key player in cancer biology. Its noteworthy potential as both a therapeutic target and a novel biomarker has been evident in predicting cancer patient prognosis, assessing levels of immune infiltration, and gauging responses to immunotherapy. This commentary aims to illuminate the multifarious functions of CD226 in cancer, delving into its impact on tumor progression, its influence on the immune response, its potential as a therapeutic target, and the persisting enigmas that drive ongoing research efforts in this domain.","PeriodicalId":72543,"journal":{"name":"Cell signaling","volume":"39 22","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell signaling","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46439/signaling.2.021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Cancer remains a significant global health challenge, with researchers continually striving to unravel the complexities of its development and progression. In recent years, CD226, also known as DNAM-1, has emerged as a key player in cancer biology. Its noteworthy potential as both a therapeutic target and a novel biomarker has been evident in predicting cancer patient prognosis, assessing levels of immune infiltration, and gauging responses to immunotherapy. This commentary aims to illuminate the multifarious functions of CD226 in cancer, delving into its impact on tumor progression, its influence on the immune response, its potential as a therapeutic target, and the persisting enigmas that drive ongoing research efforts in this domain.
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