Delayed reconstructive plastic surgery in patients with tumors of the maxillofacial region: literature review

D. Y. Azovskaya, D. Kulbakin, E. Choynzonov, D. N. Vasiliev
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Abstract

Introduction. The main treatment option for malignant neoplasms of the head and neck is combined. However, survival rates are still relatively unchanged. The surgical stage of treatment leads to extensive defects that are eliminated through reconstructive technologies. Despite the priority of performing reconstruction at the same time, delayed reconstructions are still being discussed 6–12 months after surgical treatment; therefore, it is necessary to develop new methodological and practical approaches.Aim. To determine the features of the delayed reconstructive-plastic stage in patients with malignant tumors maxillofacial region, evaluation of possible solutions for optimizing the stage.Material and methods. The analysis of available literature sources was taken in the database Medline, Pubmed, eLibrary, etc. The 101 studies were found, 60 were used to write a systematic review.Results. Delayed reconstructive plastic surgery should take into the possibility more complex and larger defects of soft and bone tissues during the reconstructive stage, previous surgery and/or radiation therapy create significant difficulties for the identification of recipient vessels. Computer-aided design (CAD)/computer-aided manufacturing (CAM) technologies allow projecting the design and positioning of reconstructive material at the preoperative stage. Mandibular reconstruction is the most difficult, that isn’t achieve only an aesthetic result, but also to restore the biomechanics of the temporomandibular joint. The development of specific complications hinders the improvement of the patient’s quality of life. In the early postoperative period is may develop necrosis of the flap, thrombosis of vascular pedicle, hematoma; in the late postoperative period plate extrusion is still one of the common complications, planning delayed reconstruction an important aspect is prevention or treatment of osteoradionecrosis. The combination of precarbohydrate loading and dalargin will allow to reduce the frequency of perioperative complications and improve the long-term results of surgical treatment.Conclusion. Reconstructive treatment in patients with defects requiring postponed reconstructive surgeries is a complex problem which requires development of an integrated approach with detailed analysis of the existing defect and previous antitumor therapy.
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颌面部肿瘤患者的延迟整形手术:文献综述
简介头颈部恶性肿瘤的主要治疗方法是综合治疗。然而,存活率仍相对较低。手术治疗阶段会导致大面积缺损,通过重建技术可以消除这些缺损。尽管同时进行重建是当务之急,但人们仍在讨论手术治疗 6-12 个月后的延迟重建;因此,有必要开发新的方法论和实用途径。确定颌面部恶性肿瘤患者延迟重建-整形阶段的特征,评估优化该阶段的可能解决方案。在 Medline、Pubmed、eLibrary 等数据库中对现有文献资料进行了分析。共找到 101 项研究,其中 60 项用于撰写系统综述。延迟重建整形手术应考虑到在重建阶段软组织和骨组织可能会出现更复杂、更大的缺损,之前的手术和/或放疗给受体血管的识别造成了很大困难。计算机辅助设计(CAD)/计算机辅助制造(CAM)技术可以在术前阶段预测重建材料的设计和定位。下颌骨重建最为困难,不仅要达到美观的效果,还要恢复颞下颌关节的生物力学。特殊并发症的出现阻碍了患者生活质量的提高。术后早期可能出现皮瓣坏死、血管蒂血栓形成、血肿;术后晚期钢板挤出仍是常见并发症之一,计划延迟重建的一个重要方面是预防或治疗骨坏死。将前碳水化合物负荷和达拉金结合起来,可以减少围手术期并发症的发生频率,改善手术治疗的长期效果。需要推迟重建手术的缺损患者的重建治疗是一个复杂的问题,需要制定综合方法,对现有缺损和之前的抗肿瘤治疗进行详细分析。
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