Investigation On the Larvicidal Potential of Endophytic Fungi Isolates from Psoralea corylifolia And Leptadenia reticulata Against Aedes Aegypti

Abstract

Globally, several million peoples are infected with epidemic-prone mosquito-borne diseases like yellow fever and malaria that is transmitted to humans by the bites of infected mosquitoes. Psoralea corylifolia, often known as babchi, is a well-liked herb that has been utilised in traditional Ayurvedic and Chinese medicine for many years for its miraculous abilities to treat a variety of skin conditions and Leptadenia reticulata, also known as Jivanti is an herb that is traditionally used in treating the conditions like malaria, diabetes, and liver disorders. The present study investigated the larvicidal properties of endophytic fungi isolated from Psoralea corylifolia and Leptadenia reticulata against Aedes aegypti. The highest larvicidal activity was seen in Trichodermata viride and Candida albicans species from leaves of L. reticulata was found to be 85.71% and 90.47 at 20 ppm. Likewise, Piriformospora indica and Aspergillus niger species from the leaves of P. corylifolia was found to be 66.66% and 83.33 % respectively. Candida albicans from leaves of L. reticulata and Aspergillus niger from the leaves of Psoralea corylifolia showed the highest mortality percentage was found to be 90.47 and 83.33 at 20 ppm respectively. The present study reveals the determination of optimal, eco-friendly, and selective mosquito larvicidal agents. The development of innovative and affordable medications to combat diseases spread by mosquitoes will be aided by more research on the isolation, characterisation, and determination of the mechanism of action against the selective mosquitos.