Shortterm and long-term results of bimammary bypass surgery in patients with multivessel coronary disease and type 2 diabetes mellitus after propensity score matching

Q4 Immunology and Microbiology Acta Biomedica Scientifica Pub Date : 2023-12-12 DOI:10.29413/abs.2023-8.5.23
A. G. Muradov, Yu. I. Grinshtein, D. Drobot, A. Miller, V. A. Sakovich
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Abstract

Background. Among patients who have undergone coronary artery bypass surgery (CABG), the proportion of people with diabetes mellitus (DM) is about 40 %. To date, the problem of choosing the optimal method of surgical myocardial revascularization, which can provide the best result in this cohort, remains completely unresolved. The aim of the study. To assess the in-hospital and long-term results of bimammary and traditional bypass surgery in patients with type 2 diabetes mellitus. Methods. From September 2018 to December 2021, 176 CABG surgeries were performed in patients with coronary heart disease (CHD) and type 2 diabetes at the Federal Center for Cardiovascular Surgery (Krasnoyarsk). Group 1 (n = 45) included patients who underwent myocardial revascularization using two mammary arteries; group 2 (n = 131) included patients who underwent myocardial revascularization using traditional technique. After propensity score matching, 45 patients were selected into each group, comparable by basic preoperative characteristics. Results. In group  1, cardiopulmonary bypass surgeries were performed in 23 (51.1 %) patients (group 1CPB), off-pump surgeries – in 22 (58.2 %) (group 1OP); in group  2, all patients underwent cardiopulmonary bypass surgeries. Hospital mortality was recorded in group 2 in 1 (2.2 %) case. Deep sternal infection developed in 1 (4.5 %) patient in group 1OP. Long-term survival in group 2 was 85.3 %, in group 1CPB – 83.3 % (p = 0.689), in group 1OP – 84.2 % (p = 0.739). 84.2 % of patients in group 2 and 100 % in groups 1CPB and 1OP had no cardiovascular events (p = 0.144 and p = 0.145, respectively). Conclusion. Bimammary bypass surgery in patients with type 2 diabetes is a safe and effective method of surgical treatment of coronary artery disease in both shortand long-term period and may be the operation of choice in patients with multivessel disease. There were no differences in patient survival up to 45 months; bimammary revascularization was associated with 100 % absence of cardiac mortality.
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多支血管冠状动脉疾病和 2 型糖尿病患者双乳搭桥手术的短期和长期效果(倾向评分匹配后
背景。在接受冠状动脉搭桥手术(CABG)的患者中,糖尿病(DM)患者的比例约为 40%。迄今为止,如何选择最佳的心肌血管重建手术方法,从而为这部分患者带来最佳治疗效果,这一问题仍未得到解决。本研究的目的评估 2 型糖尿病患者接受双乳手术和传统搭桥手术的院内和长期效果。方法。2018 年 9 月至 2021 年 12 月,联邦心血管外科中心(克拉斯诺亚尔斯克)为冠心病(CHD)和 2 型糖尿病患者实施了 176 例 CABG 手术。第一组(n = 45)包括使用双乳动脉进行心肌血运重建的患者;第二组(n = 131)包括使用传统技术进行心肌血运重建的患者。经过倾向评分匹配后,每组各选出 45 名患者,术前基本特征具有可比性。结果在第 1 组中,23 名患者(51.1%)接受了心肺旁路手术(第 1CPB 组),22 名患者(58.2%)接受了非泵手术(第 1OP 组);在第 2 组中,所有患者都接受了心肺旁路手术。第 2 组中有 1 例(2.2%)患者出现住院死亡。1OP 组有 1 例(4.5%)患者发生胸骨深部感染。第 2 组的长期存活率为 85.3%,第 1CPB 组为 83.3%(P = 0.689),第 1OP 组为 84.2%(P = 0.739)。第 2 组中 84.2% 的患者未发生心血管事件,第 1CPB 组和第 1OP 组中 100% 的患者未发生心血管事件(分别为 p = 0.144 和 p = 0.145)。结论2型糖尿病患者接受双乳旁路手术是一种短期和长期安全有效的冠状动脉疾病外科治疗方法,可作为多血管疾病患者的首选手术。患者在45个月内的存活率没有差异;双乳房血管重建手术100%不会导致心脏死亡。
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来源期刊
Acta Biomedica Scientifica
Acta Biomedica Scientifica Immunology and Microbiology-General Immunology and Microbiology
CiteScore
0.40
自引率
0.00%
发文量
106
审稿时长
7 weeks
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