Newly designed automated feedback-controlled retinal laser coagulation system

E.V. Boiko, A. A. Suetov, T. Doktorova, A. S. Izmaylov, A.A. Ivanov, A.V. Pischelin
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Abstract

Purpose. To investigate the possibility of conducting controlled laser coagulation of the retina using the feedback principle based on automated video monitoring. Material and methods. The developed automated system of laser coagulation of the retina with feedback has been tested on the fundus model in vitroand in vivoon the eyes of rabbits. The uniformity of coagulates in brightness and the required time of coagulate formation for the selected laser exposure modes were investigated. Results. On the fundus model and on the eyes of rabbits at a laser radiation power of 100, 140, 200 and 300 mW at each of the tested brightness levels in the range of 5–70% of the background value, uniform burns in brightness (coefficient of variation less than 10%) were obtained. The duration of the coagulate formation in automatic mode directly depended on the laser power: at a power of 200 and 300 mW, it did not exceed 0.3 s, at a power of 100 mW and a given brightness, it exceeded 1 s by more than 50%. With a power of 200 and 300 mW, the actual brightness was greater than planned in the range of 5–15% of the background level. With a power of 140 mW, there was no difference between the actual and planned brightness, and the duration of coagulate formation did not exceed 0.6 s with a burn brightness of 70% of the background. Conclusion. The new automated system of laser coagulation of the retina with feedback has great potential for development and implementation in clinical practice, allowing to carry out laser exposure on the fundus in vitroand in vivoto obtain reproducible threshold and near-threshold effects. Key words: retina, laser coagulation, laser system, feedback system
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全新设计的自动反馈控制视网膜激光凝固系统
目的研究利用基于自动视频监控的反馈原理对视网膜进行可控激光凝固的可能性。材料和方法。已在兔子眼底模型的体外和活体上测试了所开发的带反馈的视网膜激光凝固自动化系统。研究了所选激光曝光模式下凝固物亮度的均匀性和凝固物形成所需的时间。研究结果在眼底模型和兔子眼睛上,激光辐射功率分别为 100、140、200 和 300 mW,每个测试亮度水平在背景值的 5-70% 范围内,均可获得亮度均匀的灼伤(变异系数小于 10%)。在自动模式下,凝固形成的持续时间直接取决于激光功率:功率为 200 和 300 毫瓦时,持续时间不超过 0.3 秒;功率为 100 毫瓦且亮度一定时,持续时间超过 1 秒的比例超过 50%。当功率为 200 和 300 毫瓦时,实际亮度比计划亮度高 5-15%。功率为 140 毫瓦时,实际亮度与计划亮度之间没有差异,在燃烧亮度为背景亮度 70% 的情况下,凝结物形成的持续时间不超过 0.6 秒。结论带反馈的新型视网膜激光凝固自动化系统在临床实践中具有巨大的开发和应用潜力,可对眼底进行体外和活体激光照射,获得可重复的阈值和近阈值效应。关键词:视网膜、激光凝固、激光系统、反馈系统
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