S85 Evaluation of Quality of Life in Health by IMPACT-III in Colombian Pediatric Patients With Inflammatory Bowel Disease

V. Parra-izquierdo, J. Frías-Ordoñez, Consuelo Romero-Sanchez, F. Puentes-Manosalva, Diana Mora, John Garces, C. Cuadros, Fernando Sarmiento, Melquisedec Vargas, Carolina Samper, Mariastella Serrano
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Abstract

Background: Among patients with ulcerative colitis (UC), prior exposure to biologics or advanced therapies is associated with reduced response to future therapies, which may lead to treatment discontinuation. Therapy persistence is a proxy of real-world treatment performance and is important to achieve optimal clinical outcomes. This study compared persistence among advanced therapy-experienced patients with UC initiated on ustekinumab, an anti-interleukin 12/23 antibody, or adalimumab
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S85 通过 IMPACT-III 评估哥伦比亚儿科炎症性肠病患者的健康生活质量
背景:在溃疡性结肠炎(UC)患者中,之前接触过生物制剂或先进疗法与对未来疗法的反应降低有关,这可能会导致治疗中断。治疗持续性是真实世界治疗效果的代表,对于实现最佳临床疗效非常重要。本研究比较了有晚期治疗经验的 UC 患者在开始使用抗白细胞介素 12/23 抗体乌斯特库单抗或阿达木单抗后的持续治疗情况。
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