S142 Outcomes of Crohn’s Disease in Females: A Population-Based Study

Toy Elias, R. Beshai, Howard M. Weinberg, Ramneet Wadehra, Joshua Soliman, Petter Mounas, Priscilla Rofail
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Abstract

treatment of UC, as it indicates complete healing of the intestinal mucosa and is associated with better long-term results. Di ff erences were observed in the types of remission achieved with di ff erent therapeutic options, in fl iximab and 5-ASA were the treatments most frequently associated with deep remission, while certolizumab and adalimumab were more common in biochemical and histological remission. It is important to note sample size which was relatively small. In conclusion, this study provides strong evidence that histological remission is achievable in patients with ulcerative colitis. Theseresults supporttheimportanceof histologicalremissionas atherapeuticgoal, asit isassociated with signi fi cant clinical improvement and more favorable long-term outcomes.
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S142 女性克罗恩病的预后:基于人群的研究
这表明肠粘膜已完全愈合,长期疗效较好。不同的治疗方案所达到的缓解类型也不尽相同,iximab和5-ASA是最常见的深度缓解治疗方案,而certolizumab和阿达木单抗则更常见于生化和组织学缓解。值得注意的是,样本量相对较小。总之,这项研究提供了强有力的证据,证明溃疡性结肠炎患者可以获得组织学缓解。这些结果支持将组织学缓解作为治疗目标的重要性,因为它与显著的临床改善和更有利的长期预后相关。
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