Burden of Chronic and Heavy Opioid Use Among Elderly Community Dwellers in the U.S.

Morgan I. Bromley MPH, PhD, Easter P. Gain MSPS, Mark'Quest Ajoku MPH, Meredith A. Ray PhD, Fawaz Mzayek MD, PhD, Satish K. Kedia PhD, Xinhua Yu MD, PhD
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Abstract

Introduction

Opioid overprescribing may fuel the opioid epidemic and increase the risk of complications of opioid misuse. This study examined trends and determinants of chronic and heavy opioid use among elderly community dwellers in the U.S.

Methods

Medicare Current Beneficiary Surveys data from 2006 to 2019 were used. Common opioid medications were identified in the prescription medication files (n=47,264). Patients with Chronic users were defined as those receiving 6 or more opioid prescriptions within a year or on medication for 3 or more months, and heavy users were those having an average daily dose of 90 or more morphine milligram equivalents or 3,780 morphine milligram equivalents or more per continuous treatment episode.

Results

One in 6 elderly community dwellers ever used opioids during the study period. Chronic users were more likely to be women than men (68.9% vs 31.1%, p<0.001). Of all survey participants, 4.3% were chronic users, and 2.8% were heavy users. Among ever users, 27.7% were chronic users, and 18.1% were heavy users. The rate of opioid use rose from 12.1% in 2006, peaked at 22.8% in 2013, and decreased to 11.7% in 2019. Chronic use was 5.1%, 10.7%, and 7.6%, respectively. Heavy use was 5.5%, 10.7%, and 7.6%, respectively. However, for chronic and heavy users, there was no significant difference in the median opioid dosage and opioid duration between males and females.

Conclusions

Among elderly Medicare beneficiaries, opioid prescriptions have been decreasing since 2013. However, a substantial number of elderly people were chronic and heavy users, calling for better opioid management among them.

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美国社区老年人长期大量使用阿片类药物的负担
导言阿片类药物的过量处方可能会助长阿片类药物的流行并增加阿片类药物滥用并发症的风险。本研究调查了美国社区老年人长期和大量使用阿片类药物的趋势和决定因素。方法使用了2006年至2019年的医疗保险当前受益人调查数据。在处方药档案中确定了常见的阿片类药物(n=47,264)。慢性用药者的定义是一年内接受 6 次或以上阿片类药物处方或用药 3 个月或以上的患者,重度用药者的定义是平均每日剂量达到或超过 90 吗啡毫克当量或每次连续治疗剂量达到或超过 3,780 吗啡毫克当量的患者。长期使用者中,女性多于男性(68.9% 对 31.1%,P<0.001)。在所有调查参与者中,4.3%为长期使用者,2.8%为重度使用者。在曾经吸食者中,27.7%为长期吸食者,18.1%为大量吸食者。阿片类药物的使用率从2006年的12.1%上升到2013年的22.8%,并在2019年降至11.7%。长期使用率分别为 5.1%、10.7% 和 7.6%。重度使用者分别为 5.5%、10.7% 和 7.6%。然而,对于慢性和重度使用者,男性和女性在阿片类药物剂量中位数和阿片类药物持续时间方面没有显著差异。然而,相当多的老年人是阿片类药物的长期和大量使用者,因此需要对他们进行更好的阿片类药物管理。
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来源期刊
AJPM focus
AJPM focus Health, Public Health and Health Policy
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