Crossing barriers: the burden of inflammatory bowel disease across Western Europe.

IF 3.4 3区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY Therapeutic Advances in Gastroenterology Pub Date : 2023-12-22 eCollection Date: 2023-01-01 DOI:10.1177/17562848231218615
Aditi Kumar, Nuha Yassin, Alexandra Marley, Vittoria Bellato, Caterina Foppa, Gianluca Pellino, Pär Myrelid, Monica Millan, Beatriz Gros, Nicolas Avellaneda, Ignacio Catalan-Serra, Alaa El-Hussuna, João A Cunha Neves, Joana Roseira, Miguel F Cunha, Bram Verstockt, Dominik Bettenworth, Diane Mege, Matthew J Brookes
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Abstract

An estimated 2.5-3 million individuals (0.4%) in Europe are affected by inflammatory bowel disease (IBD). Whilst incidence rates for IBD are stabilising across Europe, the prevalence is rising and subsequently resulting in a significant cost to the healthcare system of an estimated 4.6-5.6 billion euros per year. Hospitalisation and surgical resection rates are generally on a downward trend, which is contrary to the rising cost of novel medication. This signifies a large part of healthcare cost and burden. Despite publicly funded healthcare systems in most European countries, there is still wide variation in how patients receive and/or pay for biologic medication. This review will provide an overview and discuss the different healthcare systems within Western Europe and the barriers that affect overall management of a changing IBD landscape, including differences to hospitalisation and surgical rates, access to medication and clinical trial participation and recruitment. This review will also discuss the importance of standardising IBD management to attain high-quality care for all patients with IBD.

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跨越障碍:整个西欧的炎症性肠病负担。
据估计,欧洲有 250-300 万人(0.4%)患有炎症性肠病(IBD)。虽然整个欧洲的 IBD 发病率正在趋于稳定,但患病率却在不断上升,从而给医疗系统带来了每年约 46-56 亿欧元的巨大成本。住院率和手术切除率普遍呈下降趋势,这与新型药物成本的上升背道而驰。这意味着医疗成本和负担的一大部分。尽管大多数欧洲国家都有政府资助的医疗保健系统,但患者在接受和/或支付生物药物治疗的方式上仍存在很大差异。本综述将概述和讨论西欧不同的医疗保健系统,以及影响不断变化的 IBD 整体管理的障碍,包括住院率和手术率、用药以及临床试验参与和招募方面的差异。本综述还将讨论标准化 IBD 管理的重要性,以便为所有 IBD 患者提供高质量的治疗。
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来源期刊
Therapeutic Advances in Gastroenterology
Therapeutic Advances in Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
6.70
自引率
2.40%
发文量
103
审稿时长
15 weeks
期刊介绍: Therapeutic Advances in Gastroenterology is an open access journal which delivers the highest quality peer-reviewed original research articles, reviews, and scholarly comment on pioneering efforts and innovative studies in the medical treatment of gastrointestinal and hepatic disorders. The journal has a strong clinical and pharmacological focus and is aimed at an international audience of clinicians and researchers in gastroenterology and related disciplines, providing an online forum for rapid dissemination of recent research and perspectives in this area. The editors welcome original research articles across all areas of gastroenterology and hepatology. The journal publishes original research articles and review articles primarily. Original research manuscripts may include laboratory, animal or human/clinical studies – all phases. Letters to the Editor and Case Reports will also be considered.
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