Plants Causing Toxic Myopathies

IF 1.5 3区农林科学 Q3 VETERINARY SCIENCES Veterinary Clinics of North America-Equine Practice Pub Date : 2023-12-26 DOI:10.1016/j.cveq.2023.11.001

Beatrice Sponseller DVM , Tim Evans DVM, MS, PhD

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导致中毒性肌病的植物

黄杨和梧桐枫含有次甘氨酸 A (HGA)，其毒性代谢物 MCPA-CoA 会抑制脂肪酸的 β 氧化，分别导致季节性牧场肌病 (SPM) 或非典型性肌病 (AM)。白蛇舌草和无针金线莲含有多种苯并呋喃酮（BFK）。BFKs 的特性/毒性似乎不尽相同，可能涉及毒素/毒性代谢物之间的相互作用，但最终会抑制细胞的能量代谢。秋季在稀疏草场上放牧的未节食马匹似乎很容易患上这些与植物有关的、经常致命的中毒性肌病。毒性肌病的特点是不同程度的横纹肌溶解和心肌坏死，植物毒素在干草中仍具有毒性，并随牛奶排出体外。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinary Clinics of North America-Equine Practice 农林科学-兽医学

CiteScore

2.10

自引率

9.10%

发文量

审稿时长

>36 weeks

期刊介绍： Veterinary Clinics of North America: Equine Practice presents those in the veterinary medicine field with the most current treatment of horses, updates on the latest advances, and provides a sound basis for choosing treatment options. Published 3 times a year—in April, August, and December—each issue features expert, state-of-the-art reviews on a single topic in equine practice, including gastroenterology, imaging, infectious diseases, nutrition, orthopedics, pathology, pharmacology and therapeutics, and surgery.

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