Laparoscopic and endoscopic cooperative surgery as palliative treatment for elderly patients with gastric cancer.

IF 0.9 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Nagoya Journal of Medical Science Pub Date : 2023-11-01 DOI:10.18999/nagjms.85.4.807
Masayuki Urabe, Yasuhiro Okumura, Asami Okamoto, Koichi Yagi, Yosuke Tsuji, Hiroharu Yamashita, Mitsuhiro Fujishiro, Yasuyuki Seto
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Abstract

Oncological gastrectomy, despite remaining a mainstay of gastric cancer treatment, is reportedly associated with high morbidity and mortality in elderly patients. Less invasive modalities suitable for senior gastric cancer patients with insufficient surgical tolerance are thus needed. We adopted laparoscopic and endoscopic cooperative surgery as an alternative for elderly gastric cancer cases unsuitable for aggressive gastrectomy. To date, we have experienced three cases (80-86 years old) undergoing palliative laparoscopic and endoscopic cooperative surgery. Postoperative courses were uneventful in two cases, while sutural leakage occurred in the other, which was managed conservatively. Postoperative loss of body weight and skeletal muscle mass appeared to be minimal according to bioelectrical impedance analyses. No gastric cancer recurrence was detected in any of our three cases. As to the balance between radicality and safety, laparoscopic and endoscopic cooperative surgery is potentially a viable option for geriatric gastric cancer patients in whom conventional gastrectomy is contraindicated.

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腹腔镜和内镜合作手术作为老年胃癌患者的姑息治疗方法。
据报道,肿瘤胃切除术尽管仍是胃癌治疗的主要手段,但在老年患者中却具有较高的发病率和死亡率。因此,需要适合手术耐受性不足的老年胃癌患者的微创手术方式。我们采用腹腔镜和内镜合作手术,作为不适合积极胃切除术的老年胃癌病例的替代方案。迄今为止,我们已为三例(80-86 岁)患者实施了腹腔镜和内镜合作姑息手术。其中两例术后恢复顺利,另一例出现缝合线渗漏,但采取了保守治疗。根据生物电阻抗分析,术后体重和骨骼肌质量的损失似乎很小。三例手术均未发现胃癌复发。在根治性和安全性之间取得平衡,腹腔镜和内镜合作手术可能是传统胃切除术禁忌症老年胃癌患者的可行选择。
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来源期刊
Nagoya Journal of Medical Science
Nagoya Journal of Medical Science MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
1.30
自引率
0.00%
发文量
65
审稿时长
>12 weeks
期刊介绍: The Journal publishes original papers in the areas of medical science and its related fields. Reviews, symposium reports, short communications, notes, case reports, hypothesis papers, medical image at a glance, video and announcements are also accepted. Manuscripts should be in English. It is recommended that an English check of the manuscript by a competent and knowledgeable native speaker be completed before submission.
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