[Pretreatment evaluation of CA 72.4 in patients with carcinoma of the stomach (0-IV stage) versus CEA, TPA, CA 19-9, FER].

Giornale italiano di oncologia Pub Date : 1989-04-01
F Buda, P Aragona, G Giani, R Sisto, G Di Nardo, F Binotto, P Gangemi, T De Zerbi, G Gentile, A Papadia
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Abstract

Before surgical treatments, sera of 54 pts suffering from gastric cancer, histologically typed and clinically staged (from stage 0 to 4), were assayed to evaluate CEA, TPA, CA 19-9 and Ferritin versus a new tumoral marker called TAG-72, in order to determine the biological behaviour and the relation to the clinical stage of this last one. Starting from their results, Authors say that the new marker TAG 72 has an increasing sensibility according to the clinical stage (4 th more than 1 st), and that the association of the TAG-72 plus CEA and/or TPA is rather significant in order to evaluate the evolution of the gastric cancer than other markers.

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[0-IV期胃癌患者CA 72.4与CEA、TPA、CA 19-9、FER的预处理评价]。
手术治疗前,对54例胃癌患者的血清进行组织学分型和临床分期(0期至4期),检测CEA、TPA、CA 19-9和铁蛋白与一种新的肿瘤标志物TAG-72的对比,以确定其生物学行为及其与临床分期的关系。从他们的结果出发,作者认为新的标记物TAG 72根据临床分期具有越来越高的敏感性(4 / 1大于1 / 1),并且TAG-72与CEA和/或TPA的相关性比其他标记物更能评估胃癌的发展。
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