Pathogen evolution, prevention/control strategy and clinical features of COVID-19: experiences from China

IF 3.9 3区 医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL Frontiers of Medicine Pub Date : 2023-12-29 DOI:10.1007/s11684-023-1043-5
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Abstract

Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) was reported at the end of 2019 as a worldwide health concern causing a pandemic of unusual viral pneumonia and many other organ damages, which was defined by the World Health Organization as coronavirus disease 2019 (COVID-19). The pandemic is considered a significant threat to global public health till now. In this review, we have summarized the lessons learnt during the emergence and spread of SARS-CoV-2, including its prototype and variants. The overall clinical features of variants of concern (VOC), heterogeneity in the clinical manifestations, radiology and pathology of COVID-19 patients are also discussed, along with advances in therapeutic agents.

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COVID-19 的病原体演变、预防/控制策略和临床特征:中国的经验
摘要 严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)于 2019 年年底被报道为一种世界性的健康问题,导致了非典型病毒性肺炎和许多其他器官损伤的大流行,世界卫生组织将其定义为 2019 年冠状病毒病(COVID-19)。迄今为止,该流行病被认为是对全球公共卫生的重大威胁。在本综述中,我们总结了 SARS-CoV-2 出现和传播过程中的经验教训,包括其原型和变种。我们还讨论了相关变种(VOC)的总体临床特征、COVID-19 患者临床表现的异质性、放射学和病理学,以及治疗药物的进展。
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来源期刊
Frontiers of Medicine
Frontiers of Medicine ONCOLOGYMEDICINE, RESEARCH & EXPERIMENTAL&-MEDICINE, RESEARCH & EXPERIMENTAL
CiteScore
18.30
自引率
0.00%
发文量
800
期刊介绍: Frontiers of Medicine is an international general medical journal sponsored by the Ministry of Education of China. The journal is jointly published by the Higher Education Press and Springer. Since the first issue of 2010, this journal has been indexed in PubMed/MEDLINE. Frontiers of Medicine is dedicated to publishing original research and review articles on the latest advances in clinical and basic medicine with a focus on epidemiology, traditional Chinese medicine, translational research, healthcare, public health and health policies.
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