Effect of lipiodol marking before CT-guided cryoablation on the outcome of sporadic renal cell carcinoma.

IF 1.4 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Diagnostic and interventional radiology Pub Date : 2024-03-06 Epub Date: 2024-01-02 DOI:10.4274/dir.2023.232381

Yasuhiro Ushijima, Daisuke Okamoto, Nobuhiro Fujita, Keisuke Ishimatsu, Noriaki Wada, Seiichiro Takao, Ryo Murayama, Masahiro Itoyama, Kousei Ishigami

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Abstract

Purpose: This retrospective study evaluates the impact of preoperative lipiodol marking on the outcomes of computed tomography (CT)-guided cryoablation for histologically diagnosed sporadic renal cell carcinoma (RCC).

Methods: This study analyzed the data of 173 patients who underwent CT-guided cryoablation for histologically proven sporadic RCC at a single institution between April 2014 and December 2020. The local control rate (LCR), recurrence-free survival rate (RFSR), overall survival rate (OSR), changes in renal function, and complications in patients with (n = 85) and without (n = 88) preoperative lipiodol marking were compared.

Results: The 5-year LCR and 5-year RFSR were significantly higher in patients with lipiodol marking (97.51% and 93.84%, respectively) than in those without (72.38% and 68.10%, respectively) (P value <0.01, log-rank test). There were no significant differences between the two groups regarding the 5-year OSR (97.50% vs. 86.82%) or the deterioration in chronic kidney disease stage (12.70% vs. 16.43%). Grade ≥3 complications occurred in patients with lipiodol marking (n = 2, retroperitoneal hematoma and cerebral infarction in 1 patient each) and without (n = 5; urinary fistula in 2, colonic perforation in 2, urinary infection in 1).

Conclusion: Lipiodol marking before CT-guided cryoablation for sporadic RCC is a feasible approach to improving local control and RFS while mitigating the decline in renal function. Additionally, it may help reduce complications.

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在 CT 引导下进行冷冻消融术前使用脂碘标记对散发性肾细胞癌预后的影响。

目的：这项回顾性研究评估了术前脂肪碘标记对计算机断层扫描（CT）引导下冷冻消融术治疗组织学确诊的散发性肾细胞癌（RCC）疗效的影响：本研究分析了2014年4月至2020年12月期间在一家机构接受CT引导下冷冻消融术治疗组织学证实的散发性RCC的173例患者的数据。比较了术前标记脂碘的患者（n = 85）和未标记脂碘的患者（n = 88）的局部控制率（LCR）、无复发生存率（RFSR）、总生存率（OSR）、肾功能变化和并发症：结果：进行过脂质碘标记的患者的 5 年 LCR 和 5 年 RFSR（分别为 97.51% 和 93.84%）明显高于未进行脂质碘标记的患者（分别为 72.38% 和 68.10%）（P 值结论：术前进行脂质碘标记的患者的 5 年 LCR 和 5 年 RFSR 明显高于未进行脂质碘标记的患者（P 值）：在 CT 引导下对散发性 RCC 进行冷冻消融术前进行脂肪碘标记是一种可行的方法，可在减轻肾功能下降的同时提高局部控制率和 RFS。此外，它还有助于减少并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Diagnostic and interventional radiology Medicine-Radiology, Nuclear Medicine and Imaging

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期刊介绍： Diagnostic and Interventional Radiology (Diagn Interv Radiol) is the open access, online-only official publication of Turkish Society of Radiology. It is published bimonthly and the journal’s publication language is English. The journal is a medium for original articles, reviews, pictorial essays, technical notes related to all fields of diagnostic and interventional radiology.