Safety Assessment of Butyrospermum parkii (Shea)-Derived Ingredients as Used in Cosmetics.

IF 1.2 4区 医学 Q4 PHARMACOLOGY & PHARMACY International Journal of Toxicology Pub Date : 2024-02-01 Epub Date: 2024-01-02 DOI:10.1177/10915818231224230
Christina L Burnett, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler, James G Marks, Ronald C Shank, Thomas J Slaga, Paul W Snyder, Monice Fiume, Bart Heldreth
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Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 13 Butyrospermum parkii (shea)-derived ingredients, which are most frequently reported to function in cosmetics as skin and hair conditioning agents. The Panel reviewed the available data to determine the safety of these ingredients. Because final product formulations may contain multiple botanicals, each containing similar constituents of concern, formulators are advised to be aware of these constituents and to avoid reaching levels that may be hazardous to consumers. Industry should use good manufacturing practices to limit impurities that could be present in botanical ingredients. The Panel concluded that these ingredients are safe in the present practices of use and concentration when formulated to be non-sensitizing.

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化妆品中使用的乳木果提取成分的安全性评估。
化妆品成分安全专家小组(专家小组)评估了 13 种乳木果油衍生成分的安全性,据报道,这些成分在化妆品中最常见的功能是作为皮肤和头发调理剂。专家小组审查了现有数据,以确定这些成分的安全性。由于最终产品配方可能含有多种植物成分,而每种成分都含有类似的受关注成分,因此建议配方设计师了解这些成分,避免其含量达到可能对消费者造成危害的水平。业界应采用良好的生产规范来限制植物成分中可能存在的杂质。专家小组的结论是,按照目前的使用方法和浓度,这些成分在配制成非致敏剂时是安全的。
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来源期刊
CiteScore
3.40
自引率
4.50%
发文量
53
审稿时长
4.5 months
期刊介绍: The International Journal of Toxicology publishes timely, peer-reviewed papers on current topics important to toxicologists. Six bi-monthly issues cover a wide range of topics, including contemporary issues in toxicology, safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. The Journal also publishes invited reviews on contemporary topics, and features articles based on symposia. In addition, supplemental issues are routinely published on various special topics, including three supplements devoted to contributions from the Cosmetic Review Expert Panel.
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