Racial and Ethnical Discrepancies and Similarities in the Epidemiology, Survival, and Neurological Outcomes After Acute Traumatic Spinal Cord Injury: A Retrospective Cohort Study Using Data from the NASCIS-1 Trial.

IF 2.4 Q1 REHABILITATION Topics in Spinal Cord Injury Rehabilitation Pub Date : 2023-01-01 Epub Date: 2023-11-17 DOI:10.46292/sci23-00055S
Julio C Furlan
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Abstract

Background: Little is known about the impact of race/ethnicity on the clinical and neurological outcomes after acute traumatic spinal cord injury (tSCI).

Objectives: This study examined the influence of race/ethnicity on the individuals' survival and neurological recovery within the first year after tSCI.

Methods: The 306 cases enrolled in the First National Acute Spinal Cord Injury Study (NASCIS-1) were grouped as African American individuals (n = 84), non-Hispanic White individuals (n = 159), and other races/ethnicities that included Hispanic individuals (n = 60) and Asian individuals (n = 3). Outcome measures included survival and neurological recovery within the first year after tSCI. Data analyses were adjusted for major potential confounders.

Results: There were 39 females and 267 males with mean age of 31 years who mostly sustained cervical severe tSCI after motor vehicle accidents or falls. The three groups were comparable regarding sex distribution, level and severity of tSCI, level of consciousness at admission, and total received dose of methylprednisolone. African American individuals were significantly older than non-Hispanic White individuals (p = .0238). African American individuals and individuals of other races/ethnicities more often had a tSCI with open wound caused by missile and water-related accidents than non-Hispanic White individuals (p < .0001). Survival rates within the first year after tSCI were comparable among the three groups (p = .3191). Among the survivors, there were no significant differences among the three groups regarding motor and pinprick and light-touch sensory recovery (p > .0500).

Conclusions: The results of this study suggest that, while there were few differences among the racial/ethnical groups regarding the epidemiology of tSCI, race/ethnicity did not influence survival rate or neurological recovery within the first year post-tSCI.

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急性创伤性脊髓损伤后的流行病学、存活率和神经系统结果中的种族和人种差异与相似性:使用 NASCIS-1 试验数据的回顾性队列研究。
背景:人们对种族/民族对急性创伤性脊髓损伤(tSCI)后临床和神经系统结果的影响知之甚少:本研究探讨了种族/民族对急性创伤性脊髓损伤后第一年内患者存活率和神经功能恢复的影响:第一次全国急性脊髓损伤研究(NASCIS-1)中登记的 306 个病例被分为非裔美国人(n = 84)、非西班牙裔白人(n = 159)和其他种族/民族,其中包括西班牙裔(n = 60)和亚裔(n = 3)。结果测量包括 tSCI 后第一年内的存活率和神经功能恢复情况。数据分析对主要的潜在混杂因素进行了调整:结果:共有 39 名女性和 267 名男性,平均年龄为 31 岁,他们大多因机动车事故或跌倒导致颈椎重度损伤。三组患者在性别分布、颈椎重度损伤的程度和严重性、入院时的意识水平以及甲基强的松龙的总剂量方面具有可比性。非裔美国人的年龄明显高于非西班牙裔白人(p = .0238)。与非西班牙裔白人相比,非裔美国人和其他种族/族裔的人更常因导弹和与水有关的事故导致开放性伤口的创伤性脑损伤(p < .0001)。三个群体在创伤后第一年内的存活率相当(p = .3191)。在幸存者中,三组在运动、针刺和轻触感觉恢复方面没有显著差异(p > .0500):本研究的结果表明,虽然不同种族/族裔群体在创伤后脊髓损伤的流行病学方面差异不大,但种族/族裔并不影响创伤后脊髓损伤后第一年内的存活率或神经功能恢复。
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来源期刊
CiteScore
3.20
自引率
3.40%
发文量
33
期刊介绍: Now in our 22nd year as the leading interdisciplinary journal of SCI rehabilitation techniques and care. TSCIR is peer-reviewed, practical, and features one key topic per issue. Published topics include: mobility, sexuality, genitourinary, functional assessment, skin care, psychosocial, high tetraplegia, physical activity, pediatric, FES, sci/tbi, electronic medicine, orthotics, secondary conditions, research, aging, legal issues, women & sci, pain, environmental effects, life care planning
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