Feasibility of abdominal fat quantification on MRI and impact on effectiveness of abdominal compression for radiotherapy motion management

M. Daly , L. McDaid , C. Nelder , R. Chuter , A. Choudhury , A. McWilliam , G. Radhakrishna , C.L. Eccles
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Abstract

The impact of fat on abdominal compression effectiveness in abdominal cancers was determined using magnetic resonance imaging (MRI). Visceral and subcutaneous fat were delineated on T2W 3D MRI, and motion change with compression was measured on 2D cine MRI. Results from 16 participants showed no correlation between fat percentage, body mass index (BMI), and motion change. Median BMI was 28.7 (SD, 4.9). Mean motion reduction was 7.8 mm (IQR, 5.0; p = 0.001) with compression. While no direct link was found between fat, BMI, and compression effectiveness, abdominal compression remains crucial for motion management in radiotherapy planning, providing dosimetric benefits.

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核磁共振成像中腹部脂肪量化的可行性及对放射治疗运动管理中腹部加压效果的影响
利用磁共振成像(MRI)确定了脂肪对腹部癌症患者腹部压迫效果的影响。内脏和皮下脂肪在 T2W 三维核磁共振成像上进行了划定,压缩时的运动变化在二维电影核磁共振成像上进行了测量。16 名参与者的研究结果表明,脂肪百分比、体重指数 (BMI) 和运动变化之间没有相关性。体重指数中位数为 28.7(标准差,4.9)。压缩后的平均运动减少量为 7.8 毫米(IQR,5.0;P = 0.001)。虽然在脂肪、体重指数和压迫效果之间没有发现直接联系,但腹部压迫对于放疗计划中的运动管理仍然至关重要,并能提供剂量学优势。
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CiteScore
4.10
自引率
0.00%
发文量
48
审稿时长
67 days
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