Impact of anabolic androgenic steroids on COVID-19

IF 2.1 4区 医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Steroids Pub Date : 2024-01-03 DOI:10.1016/j.steroids.2023.109361
Khaja Moinuddin shaik, Vijay Patibandla, Sukhendu Nandi
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Abstract

In the wake of the Novel Coronavirus arrival, the world witnessed the fragility of healthcare systems and the resilience of healthcare workers who stood on the front lines. SARS-CoV-2, also known as COVID-19 or severe acute respiratory syndrome, first appeared in China in December 2019. The infection quickly spread across the nation and the world. All countries severely restricted social interaction to stop the virus's transmission, impacting all sporting, social, and recreational activities. Anabolic androgenic steroids (AASs) are frequently used illegally to enhance strength and physical attractiveness. However, they could hurt immune system health. Much research hasn't been done yet on the connection between Covid-19 and AASs. Synthetic testosterone analogs known as anabolic androgenic steroids (AASs) can have an immune-system-altering effect. Sportspeople and bodybuilders are vulnerable to AAS abuse. Governmental reactions to the coronavirus infection issue over the last year have drawn much attention and discussion regarding public services, the experience and lessons learned from different limitations, and strategies for dealing with potential future pandemics. Using AAS has the potential to cause a variety of adverse reactions, including cardiovascular issues (including high blood pressure, heart disease, and blood clots), liver damage, renal failure, mood swings, aggressiveness, and psychiatric disorders. Individuals already suffering from severe respiratory conditions like COVID-19 may have these risks increased. This review mainly highlights the anabolic androgen steroids use and its unseen effects on coronavirus patients and gymnastics.

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合成代谢雄性类固醇对 COVID-19 的影响。
新型冠状病毒来袭之后,世界见证了医疗系统的脆弱和站在前线的医护人员的坚韧。SARS-CoV-2 又称 COVID-19 或严重急性呼吸系统综合征,于 2019 年 12 月首次在中国出现。感染迅速蔓延至全国乃至全世界。所有国家都严格限制社会交往以阻止病毒传播,影响了所有体育、社交和娱乐活动。合成代谢雄性类固醇(AAS)经常被非法用于增强力量和身体吸引力。然而,它们可能会损害免疫系统的健康。关于 Covid-19 和合成雄性类固醇之间的联系,目前还没有很多研究。被称为合成代谢雄性类固醇(AASs)的合成睾酮类似物会对免疫系统产生影响。运动员和健美运动员很容易滥用 AAS。去年,政府对冠状病毒感染问题的反应引起了人们对公共服务、不同限制条件下的经验和教训以及应对未来可能发生的流行病的策略的广泛关注和讨论。使用兴奋剂有可能导致各种不良反应,包括心血管问题(包括高血压、心脏病和血栓)、肝损伤、肾衰竭、情绪波动、攻击性和精神失常。已经患有 COVID-19 等严重呼吸系统疾病的人可能会增加这些风险。本综述主要强调合成代谢雄性类固醇的使用及其对冠状病毒患者和体操产生的看不见的影响。
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来源期刊
Steroids
Steroids 医学-内分泌学与代谢
CiteScore
5.10
自引率
3.70%
发文量
120
审稿时长
73 days
期刊介绍: STEROIDS is an international research journal devoted to studies on all chemical and biological aspects of steroidal moieties. The journal focuses on both experimental and theoretical studies on the biology, chemistry, biosynthesis, metabolism, molecular biology, physiology and pharmacology of steroids and other molecules that target or regulate steroid receptors. Manuscripts presenting clinical research related to steroids, steroid drug development, comparative endocrinology of steroid hormones, investigations on the mechanism of steroid action and steroid chemistry are all appropriate for submission for peer review. STEROIDS publishes both original research and timely reviews. For details concerning the preparation of manuscripts see Instructions to Authors, which is published in each issue of the journal.
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