A Perspective Review of Cancer Therapy (Part I): Immunotherapy, Gene Therapy, and Nanotechnology

Alberto Pajuelo
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Abstract

The application of genomic profiling approaches has propelled the advancement of precision medicine, enabling the development of personalized treatment programs that are specifically customized for each particular patient. This method considers the distinct genetic composition of each tumor, allowing for the detection of crucial driver mutations and possible weaknesses that might be targeted for therapeutic purposes. Furthermore, immunotherapy has emerged as a promising approach in cancer treatment, utilizing the potential of the immune system to identify and eradicate cancerous cells. Medical breakthroughs like CAR-T cell therapy have already demonstrated exceptional efficacy in treating hematologic malignancies. Moreover, state-of-the-art technologies such as CRISPR-Cas9 gene editing offer potential for directly altering tumor cells or augmenting the efficacy of current treatments. The future of cancer therapy is focused on developing more precise and targeted techniques to enhance patient outcomes and ultimately overcome this destructive illness. This involves continual research and cooperation among scientists, physicians, and pharmaceutical corporations on a worldwide level.
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癌症疗法透视回顾(第一部分):免疫疗法、基因疗法和纳米技术
基因组剖析方法的应用推动了精准医疗的发展,使为每位特定患者量身定制的个性化治疗方案成为可能。这种方法考虑了每个肿瘤的不同基因组成,可以检测出关键的驱动突变和可能的弱点,从而有针对性地进行治疗。此外,免疫疗法利用免疫系统的潜力来识别和消灭癌细胞,已成为治疗癌症的一种有前途的方法。CAR-T 细胞疗法等医学突破已在治疗血液系统恶性肿瘤方面显示出卓越的疗效。此外,CRISPR-Cas9 基因编辑等最先进的技术也为直接改变肿瘤细胞或增强现有疗法的疗效提供了可能。未来癌症治疗的重点是开发更精确、更有针对性的技术,以提高患者的治疗效果,并最终战胜这一毁灭性疾病。这需要科学家、医生和制药公司在全球范围内开展持续的研究与合作。
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