A review on molecular breeding techniques: Crucial approach in livestock improvement

Rupak Kandel, Ishwari Prasad Kadariya, Kailash Bohara, Sonu Adhikari
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Abstract

For underdeveloped countries, molecular breeding (MB) has a lot of promise. However, the implementation in developing countries is far from uniform. Livestock improvement programs aim to improve the genetics of domesticated animal populations by selecting males and females who, when mated, will produce progeny that perform better than the current generation's average. The amount of genetic progress made through conventional selection and breeding methods for quantitative traits in livestock is successful, but limitations such as routinely recording phenotypes, animal sacrifice for meat quality traits, recording in particular sex for sex-limited traits, and so on the limit the amount of genetic progress made through conventional selection and breeding methods. Marker-assisted selection (MAS), genome-wide selection (GWS), marker-assisted recurrent selection (MARS), and genome-wide sequencing (GS) are examples of modern breeding procedures. Molecular genetics technology may provide a technique to choose breeding animals at an early age (even embryos), to select for a wide variety of features and to improve the accuracy of forecasting an individual's mature phenotype. This paper examines the challenges and potential of applying molecular breeding techniques to improve livestock in developing countries.
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分子育种技术综述:家畜改良的关键方法
对于不发达国家来说,分子育种(MB)大有可为。然而,发展中国家的实施情况远非如此。家畜改良计划旨在通过选择雄性和雌性家畜,使其交配后产生的后代表现优于当代平均水平,从而改善驯养家畜种群的遗传学。通过传统的牲畜数量性状选育方法取得的遗传进展是成功的,但常规的表型记录、肉质性状的动物牺牲、特定性别性状的记录等局限性限制了传统选育方法取得的遗传进展。标记辅助选择(MAS)、全基因组选择(GWS)、标记辅助重复选择(MARS)和全基因组测序(GS)都是现代育种程序的实例。分子遗传学技术可为早期(甚至胚胎)选择育种动物、选择各种特征以及提高预测个体成熟表型的准确性提供技术手段。本文探讨了应用分子育种技术改良发展中国家牲畜所面临的挑战和潜力。
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